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姜正清, 胡薇, 张莉, 冯宗亮, 刘石柱, 何益新, 周枫, 秦光明, 尹潞, 陈康林, 邢辉, 阮玉华, 邵一鸣. 静脉吸毒人群HIV阳转率与队列保持影响因素[J]. 中国公共卫生, 2005, 21(11): 1289-1291. DOI: 10.11847/zgggws2005-21-11-06
引用本文: 姜正清, 胡薇, 张莉, 冯宗亮, 刘石柱, 何益新, 周枫, 秦光明, 尹潞, 陈康林, 邢辉, 阮玉华, 邵一鸣. 静脉吸毒人群HIV阳转率与队列保持影响因素[J]. 中国公共卫生, 2005, 21(11): 1289-1291. DOI: 10.11847/zgggws2005-21-11-06
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JIANG Zhengqing, HU Wei, ZHENG Li, . HIV incidence and factors associated with retention in a 12-month follow-up study of injection drug users in Xichang County[J]. Chinese Journal of Public Health, 2005, 21(11): 1289-1291. DOI: 10.11847/zgggws2005-21-11-06
Citation: JIANG Zhengqing, HU Wei, ZHENG Li, . HIV incidence and factors associated with retention in a 12-month follow-up study of injection drug users in Xichang County[J]. Chinese Journal of Public Health, 2005, 21(11): 1289-1291. DOI: 10.11847/zgggws2005-21-11-06
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静脉吸毒人群HIV阳转率与队列保持影响因素

HIV incidence and factors associated with retention in a 12-month follow-up study of injection drug users in Xichang County

    摘要
  • 摘要:
      目的   了解静脉吸毒人群HIV血清抗体阳转率和队列本底的社会人口学和高危行为特征以及6个月随访情况与队列12个月保持率的关系.
      方法   于2002年11月, 在四川省西昌市从社区筛查HIV抗体阴性的静脉吸毒人群前瞻性研究队列333人.在队列每6个月随访时进行HIV抗体检测来估算HIV血清抗体阳转率和分析队列本底的社会人口学和高危行为特征以及6个月随访情况与队列12个月保持率的关系.
      结果   静脉吸毒人群队列12个月的HIV血清抗体阳转率为3.17×10-2人年(95%CI=0.98~5.37)和保持率为70.3%.在多因素Logistic回归分析中, 与队列12个月保持率差异有统计学意义的变量为6个月能随访到(OR=8.74, 95%CI=4.95~15.41;P < 0.0001)和彝族(OR=0.50, 95%CI=0.28~0.87;P < 0.0151).未见静脉吸毒人群队列本底的HIV高危行为因素与队列12个月保持率的关系差异有统计学意义.
      结论   静脉吸毒人群HIV血清抗体阳转率彝族和6个月未随访到的吸毒人群队列12个月的保持率低.

     

    Abstract:
      Objective   To understand HIV incidence and retention by subject's baseline sociodemog raphic and behavio ral characteristics in a 12-month follow-up study of injection drug users.
      Methods   During November 2002, a communitybased baseline survey was conducted to recruit333HIV sero-negative injection drug users(IDUs)for a prospective cohortstudy in Xichang County of Sichuan Province, China.
      Results   During the first12-month follo w-up period, HIV incidence was 3.17 per 100 person-years95% confidence interv al(CI):0.98, 5.37.The retention r ate atthe 12-month follow up visitwas 70.3%.In a multiple logistic regression model, appearing at6-month follow-up visit(OR=8.74, 95% CI 4.95~15.41;P < 0.0001)and Yi ethnicity(OR=0.50, 95% CI 0.28~0.87;P < 0.0151)were independently asso ciated with retention in a 12-month follow-up study of injection drug users.No drug using and sexual behaviors were found to be associated with retention atthe 12-month follow-up visit.
      Conclusion   There is a high HIV incidence among IDUs in Xichang County of Sichuan province, China; Yiethnicity has a lower retention rate and appearing at 6-month follow-up visitmay predictlong-term retention rate in IDUs cohort, respectively.

     

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