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杜莹, 王晓燕, 解清, 欧阳荔, 魏雪涛, 王京宇. 富硒蛋白对小鼠免疫功能影响[J]. 中国公共卫生, 2006, 22(1): 84-85. DOI: 10.11847/zgggws2006-22-01-44
引用本文: 杜莹, 王晓燕, 解清, 欧阳荔, 魏雪涛, 王京宇. 富硒蛋白对小鼠免疫功能影响[J]. 中国公共卫生, 2006, 22(1): 84-85. DOI: 10.11847/zgggws2006-22-01-44
DU Ying, WANG Xiaoyan, XIE Qing, . Effect of selenium-enriched protein on immune function of mice[J]. Chinese Journal of Public Health, 2006, 22(1): 84-85. DOI: 10.11847/zgggws2006-22-01-44
Citation: DU Ying, WANG Xiaoyan, XIE Qing, . Effect of selenium-enriched protein on immune function of mice[J]. Chinese Journal of Public Health, 2006, 22(1): 84-85. DOI: 10.11847/zgggws2006-22-01-44

富硒蛋白对小鼠免疫功能影响

Effect of selenium-enriched protein on immune function of mice

  • 摘要:
      目的   观察富硒蛋白对正常小鼠免疫功能的影响作用.
      方法   选用48只健康的ICR小鼠, 随机分成4组, 在饲料中分别加入贫硒蛋白、贫硒蛋白与亚硒酸钠混合物、富硒牛奶、富硒蛋白, 进行30 d的喂饲后测定小鼠淋巴器官指数、迟发型变态反应、溶血空斑形成数.
      结果   富硒蛋白能够促进小鼠溶血空斑的形成, 刺激迟发型变态反应, 作用优于相同硒含量的富硒牛奶或者贫硒蛋白与无机硒的混合饲料(P < 0.05).
      结论   该富硒蛋白产品有提高小鼠体液免疫、细胞免疫功能的作用.

     

    Abstract:
      Objective   To study the influence of selenium-enriched proteins, which were made from selenium-enriched milk, on the immune function of the health mice.
      Methods   For ty-eighthealthy mice were chosen and randomly divided into 4 groups:nor mal milk g roup, normal milk+inorg anic selenium(Na2SeO3)group, selenium-enriched milk group, seleniumenriched protein group.30days later, the index of lymphoid organ of mice, delayed-type hypersensitivity(DTH), the number of plague forming cell were determined, respectively.
      Results   The selenium-enriched protein could increase the number of plague forming cell(PFC), and stimulated DTH.Its influence on the immune of the mice was stronger than those form normal milk+inorganic selenium group and selenium-enriched milk group under the same dosage.
      Conclusion   The seleniumenriched protein can improve cellular immunity and humoral immunity of mice.

     

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