Objective   To discuss the primary influence factors and interventions of univeysity students'life quality.

  Methods   1171 Students who major in engineering, management or medicine were asked to fill in WHO's Quality of Life (WHOQOL)-100 and the self-made "influential factors questionnaire".Variable were set as whole life quality, general health situation and the 6 fields of life quality.All scores were processed by logistical regression analysis through monovariate and multivariate.

  Results   Excepting the field of spiritual support, classificatory calculating accuracy of 6 models in order were 97.1%, 94.9%, 96.2%, 98.6%, 69.6 and 97.7%.There were 15 factors that influence life quality of univeysity students.The top six primary factors were currenthealth situation, interests in one's major, network motivation, monthly expenditure, gender, and distressed of co-relations.Other factors were studying expectations, real achievement, Grades, Majors, unable to act as monitor, suspending one's schooling for certain reasons, getting punishment for some reasons, failure in examination and parents'education degree.

  Conclusion   The life quality of college students are influenced by such factors as individual, university, family and society.The interventions should be focused on strengthening physical health, cultivating positive attitudes and improving economical situation.