Abstract: ObjectiveTo study the effect of comprehensive community interv ention on the improvement of the blood sugar and blood-lipid profile and quality of life in patients of diabetic with coronary heart disease(CHD).MethodsOne hundred and fifty-eight cases of diabetic with CHD patients were randomized into two groups:community intervention group (87 cases)and control group(71 cases).Regular and fixed-time monitoring was carried out and home-visit follow-up and interventional measures were instituted for the intervention group.There were no changes forex isting drug use of the two groups.ResultsTwo groups were compared prospectively.The baseline data of the intervention group were:FBG(8.45±2.97) mmol/L,cholesterol(TC)(6.38±1.25)mmol/L,triglyceride(TG)(1.86±0.86)mmol/L,high density lipoprotein cholesterol(HDL-C)(1.38±0.81)mmol/L,low density lipoprotein cholesterol(LDL-C)(4.02±1.39)mmol/L.After comprehensive intervenion for a year,the TC was(5.27±0.98)mmol/L,TG was(1.40±0.19)mmol/L,HDL-C was(2.01±0.65) mmol/L and LDL-C was(1.61±0.95)mmol/L.A significant difference was observed before and after intervention(P<0.05)in the intervention group.There was also a significant difference between the two groups(P<0.05).The disablement rate(0)and case-fatality rate(1.16%)after a year,the rate in the intervention group were much lower than that of control group(7.14% and 5.71%),The difference was significant(P<0.001).The quality of life,compliance and life satisfaction of patients in the intervention group improved,which were significant compared with the control group(P<0.01)after one year intervention.ConclusionComprehensive community inter vention can improve the blood sug ar,blood-lipid and quality of life to the patients who lock into the disease of diabetic patients with coronary heart disease(CHD),this should become a new medical modality in the prevention and treatment of diabetic patients with coronary heart disease.