Abstract: ObjectiveTo understand the current situation of AIDS knowledge and to explore the effective intervention.MethodsStratified cluster sampling was used to investigate villagers with questionnaire.ResultsGenerally,drivers had poor AIDS prevention knowledge.Only 65.19% people knows 3 kinds of AIDS relay approaches,97.28% of truck divers hope having know ing more AIDS knowledge.The nature partner relation of them was complicated,but only 61.44% person persisted in using a condom when sexual behaviour happened in the female serves.Though nothaving checked up HIV infected person,HBV and syphilis spirochaete infection inspect up out rates being 13.62% and 0.78%.ConclusionTruck drivers high-risk behavioris common,who is the high-risk groups of HIV infection.Integretive AIDS education must be intensified and the self-protective abilities to control AIDS being spread toward general crowd by dangerous crowd.