Abstract: ObjectiveTo study common allergens and provide basis for the prevention and treatment of children allergic diseases.MethodsUsing automatic in vit ro immunity diagnosis meter(UniCAP100),9 kinds of inhalation allergens and 8 kinds of food allergens were tested in 2,276 children allergy cases.The positive rate of each kind of allergen,the seasonal distribution of allergic diseases in children and the sex differences of positive rates of allergens among children were analyzed.ResultsDermatophagoides farinae,dermatophagoides pteronyssinus and house dust are the main inhalation allergens and the positive rates of them are 76.02%,75.46% and 62.37% respectively.Other allergens are cockroaches,mothes,amaranthes, cajeputs,horsetail beefwoods and mulberry trees.The main food allergens are eggs and milk and the positive rates of them are 49.58% and 46.66% respectively.Other food allergens are wheat,shrimps,peanuts,soybean,crabs and fishes.The seasonal distribution of allergic diseases in children demonstrated that there were two periods in a year,the early winter(Nov.,Dec.) and the spring(Mar.,Apr.),in which children tend to suffer from allergens more frequently than any other periods.ConclusionIn Shenzhen,dermatophagoides farinae,dermatophagoides pteronyssinus and house dusts are the main inhaliation allergens and eggs and milk are the main food allergens.As a whole,the harmfulness of inhalation allergens is higher than food allergens.The prevention and treatment of allergic diseases in children should be paid much more attention to in the early winter and spring in a year.