Abstract: Objective To explore non-biologic risk factors of lowbirth weight and the evidence for intervention to decrease the incidence of lowbirth weight(LBW).Methods A case-control study with 896 pregnant women was conducted in Fujian pro vincial maternity and children's hospital from Sept.2004 to June 2006 using simple and multivariate logistic reg ression models.Results The determinants of LBW included loweducation,lowincome,unstable occupation,husbands.smoking and drinking,less health education of pregnant women,husbands.anxiety,less and late examination of pre-pregnancy.While the husbands' watching TV at home was a protecting factor.Conclusion Improving the situation of economy and health education,good behavior of pregnant women and their husbands can decrease the risk of LBW.