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观晓辉, 范碧惠, 李韶光. 成人非酒精性脂肪性肝病与代谢综合征关系[J]. 中国公共卫生, 2009, 25(7): 829-830. DOI: 10.11847/zgggws2009-25-07-31
引用本文: 观晓辉, 范碧惠, 李韶光. 成人非酒精性脂肪性肝病与代谢综合征关系[J]. 中国公共卫生, 2009, 25(7): 829-830. DOI: 10.11847/zgggws2009-25-07-31
GUAN Xiao-hui, FAN Bi-hui, LI Shao-guan. Relationship between nonalcoholic fatty liver disease and metabolic syndrome in adults[J]. Chinese Journal of Public Health, 2009, 25(7): 829-830. DOI: 10.11847/zgggws2009-25-07-31
Citation: GUAN Xiao-hui, FAN Bi-hui, LI Shao-guan. Relationship between nonalcoholic fatty liver disease and metabolic syndrome in adults[J]. Chinese Journal of Public Health, 2009, 25(7): 829-830. DOI: 10.11847/zgggws2009-25-07-31

成人非酒精性脂肪性肝病与代谢综合征关系

Relationship between nonalcoholic fatty liver disease and metabolic syndrome in adults

  • 摘要: 目的 研究成人非酒精性脂肪性肝病 (NAFLD)与代谢综合征 (MS)的关系.方法 以175例NAFLD患者为病例组,54名非脂肪性肝病体检者为对照组,检测2组的收缩压 (SBP)、舒张压 (DBP)、腰围 (WI)、甘油三酯 (TG)、空腹血糖 (FBG)、高密度脂蛋白胆固醇 (HDL-C).结果 病例组WI、SBP、TG、FBG等指标均高于对照组 (分别,t=3.790,3.688,2.825,3.251,3.429,2.635,均P<0.01);HDL-C低于对照组 (t=2.849,P<0.01);中心性肥胖、高血压、高TG血症、低HDL-C血症、高血糖及MS的患病率高于对照组 (分别χ2=29.02,8.64,11.37,6.51,11.72,9.65,均P<0.01),合并MS组分≥3项者的比例高于对照组 (χ2=6.15,P<0.05),合并MS组分≤1项者的比例低于对照组 (χ2=26.29,P<0.01).结论 NAFLD是MS的组成成分之一,NAFLD可用于预测代谢紊乱危险因素的聚集.

     

    Abstract: Objective To study the relationship between nonalcoholic fatty liver disease (NAFLD) and metabolic syndrome (MS)in adults.Methods Overall 175 NAFLD patients and 54 non-fatty liver adults were assigned as survey group and contrast group.The levels of systolic blood pressure (SBP),diastolic blood pressure (DBP),waistline (WI),triglyceride (TG),fasting blood glucose (FBG),high density lipoprotein cholesterol (HDL-C) were tested and analyzed.Results The levels of SBP,DBP,WI,TG,FBG in survey group were significantly higher than those in contrast group (t=3.790,3.688,2.825,3.251,3.429,2.635,P<0.01).The level of HDL-C in survey group was significantly lower than that of in contrast group (t=2.849,P<0.01).Central obesity,high blood pressure,high blood triglyceride,low high density lipoprotein and hyperglycemia in survey group were significantly higher than those in contrast group (χ2=29.02,8.64,11.37,6.51,11.72,9.65,P<0.01).The proportion of the patients with three or more than three components of MS in survey group was significantly higher than that of in contrast group (χ2=6.15,P<0.05).And the proportion of the patients with one or without component of MS in survey group was significantly lower than that of in contrast group (χ2=26.29,P<0.01).Conclusion NAFLD is a component of MS.NAFLD could be a predictor for metabolic disorder.

     

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