Abstract: Objective To preliminarily build a system of indexes for evaluating information system's supporting ability in infectious disease control.Methods Interviews and questionnaire study on the demand of institutions involved in the disease control were conducted to acquire system function and current situation.Then analyses on directly related demand of infectious disease control were carried out in respects of priority,difficulty,and risk.Finally,composite evaluation of information supporting ability was done according to future demand characteristics.Results In all 33 items,4 types of main infectious disease control function demand were obtained and a system of indexes for ability evaluation was preliminarily founded with 8 dimensions and 5 hierarchies.Conclusion The evaluating indexes and scoring standard could be applied effectively in assessing the supporting ability and maturity of information system in infectious disease control.