毕节市人群乙肝感染状况及血氟含量检测

HBV infection and serum fluoride among healthy population in Bijie, Guizhou

摘要: 目的了解贵州省毕节地区燃煤污染型地方性氟中毒非干预区-鸭池镇下坝村与干预区-长春镇长春乡人群的乙型肝炎病毒(HBV)感染状况与流行趋势以及血氟含量。方法采用酶联免疫吸附试验(ELISA)方法进行HBV血清学标志物检测,酶标仪分析HBV血清学结果;采用氟离子选择电极法测定血氟含量。结果共调查汉族人群532人,检出HBV感染403例,感染率高达75.75%;其中高血氟人群检出HBV感染326例,感染率为68.78%;正常血氟人群检出HBV感染42例,感染率为65.63%。结论贵州毕节鸭池镇下坝村与长春镇长春乡均具有较高的HBV感染率及血氟含量。

Abstract: Objective To investigate the prevalence of HBV infection and serum fluoride among healthy people in Bijie.Methods Serum fluoride and HBV serum markers were tested in 532 people.Results An overa llHBV infection prevalence of 75.75% was found with prevalences of 68.78% in people of high serum fluoride and 65.73% in people of normal serum fluoride.There was no significant difference in prevalence rate between the males and females(P>0.05).Conclusion The prevalence rate of HBV infection in Bijie is higher than that in healthy population of Libo and Weining in Guizhou.