Abstract: Objective To analyze the prevalence and immunization level of measles in the general population and explore the controlling strategy of measles epidemic in Hami region.Methods The epidemiological characteristics was analyzed based on the incidence data of measles in Hami region in 2008.Results The outbreak coexisting with a highly sporadic measles epidemic presented in Hami region in 2008.A total of 440 cases of measles were reported with an incidence rate of 96.22/100 000.The measles cases were mainly adults over the age of 19 and infants under the age of 4.Among the reported cases,374 cases were elder than required month age for attenuated live measles vaccine(≥8 months);72 (19.25%)had mimunization history and 151(40.37%)had no immunization history.Conclusion Infants with deficient antibody from mother and adults with low antibody level are the susceptible population of measles.