Abstract: Objective To understand the status and influence of HIV/AIDS cases among immigrant women in Shandong province and provide a scientific basis for controlling the transm ission of HIV/AIDS.Methods Epidemiology investigation and active follow-up were conducted among immigrant women from 2003 to 2006.Statistical analysis of data was performed with SPSS 11.5.Results By the end of June 2006,312 HIV/AIDS cases were found among the immigrant women,which accounted for 24.4% of all cases and 56.8% of female cases in the province.There were 56 cases who transmitted HIV to their spouse through sexual intercourse,11 cases were mother to child transmission.Conclusion HIV/AIDS is still on the rise among immigrant women and there is the second generation of HIV transmission.The HIV/AIDS cases among immigrant women affect the HIV/AIDS epidemic situation in Shandong province.