Abstract: Objective To explore the association of alcohol dependence and high risk sexual behavior among coal miners.Methods With cluster sampling,1180 coal miners were surveyed with questionnaire about alcohol dependence (MAST)and high risk sexual belavior in two mines of Huainan in Anhui province.Results The prevalence of a lcohol drinking was 85.51% in miners and the prevalence of alcohol dependence was 94.1% in the drinking miners.With increasing aggravation of alcohol dependence status,the incidence rate of sexual intercourse outside marriage raised(OR=1.55,χ_trend²=35.02,P=0.00)while the incidence rate of using condom in sexual intercourse outside marriage decreased(OR=1.801,χ_trend²=8.45,P=0.00).Conclusion Improving alcohol dependence status may be an effective way to prevent high risk sexual behavior for prevention of sexually transm itted disease among coal miners.