高级检索
刘丽花, 杨丽华, 赵欣荣, 李秀娟, 周红, 徐宝红. 不同途径感染人群HIV-1亚型分布[J]. 中国公共卫生, 2009, 25(8): 1023-1024. DOI: 10.11847/zgggws2009-25-08-72
引用本文: 刘丽花, 杨丽华, 赵欣荣, 李秀娟, 周红, 徐宝红. 不同途径感染人群HIV-1亚型分布[J]. 中国公共卫生, 2009, 25(8): 1023-1024. DOI: 10.11847/zgggws2009-25-08-72
shu
LIU Li-hua, YANG Li-hua, ZHAO Xin-rong, . Subtype distribution of HIV-1 among different people infected[J]. Chinese Journal of Public Health, 2009, 25(8): 1023-1024. DOI: 10.11847/zgggws2009-25-08-72
Citation: LIU Li-hua, YANG Li-hua, ZHAO Xin-rong, . Subtype distribution of HIV-1 among different people infected[J]. Chinese Journal of Public Health, 2009, 25(8): 1023-1024. DOI: 10.11847/zgggws2009-25-08-72
shu

不同途径感染人群HIV-1亚型分布

Subtype distribution of HIV-1 among different people infected

    摘要
  • 摘要: 目的 了解河北省石家庄市不同感染人群人类免疫缺陷病毒I型(HIV-1)亚型及分布特点。方法 从石家庄市报告的148例HIV-1抗体阳性者抗凝全血中提取前病毒DNA,用套式聚合酶链反应(nested-PCR)扩增病毒膜蛋白(ENV)基因的C2-V3区并进行序列测定,与国际标准参考序列比较确定亚型。结果 148例样品分属8个亚型,45例为欧美B,37例为CRF07-BC,35例为泰国B(B'),25例为CRF01-AE,C和CRF02-AG各2例,CRF03-AB和CRF11-CPX各1例。结论 既往供受血人员和注射吸毒人群感染的HIV-1亚型相对单一,性传播亚型分布较广。

     

    Abstract: Objective To investigate the subtypes and distribution characteristics of HIV1 among different populations infected.Methods HIV1 proviral DNA was extracted from the whole blood of 148 HIV1 infected indi iduals.The HIV-1env C2-V3 gene region was amplified by nested PCR and was sequenced.The sequence was compared with HIV-1 subtype reference sequence.Results There were 8 kinds of HIV-1 subtypes in 148 samples.In the subjects,45 case swere Bsubtype;37 were CRF07 BC;35 were B';25 were CRF01-AE;2 cases were C and CRF02-AG;1case was CRF03-AB and CRF02-AG.Conclusion HIV-1 subtypes in the blood donors and blood recipients and in drug users were not very different.Sexually transmitted HIV-1 subtype was distributed widely.

     

    • HTML全文
    • 参考文献(0)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回