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彭仙娥, 黄之敏, 林建银, 陆青青, 林俊, 林旭. 职员非酒精性脂肪肝患病及影响因素分析[J]. 中国公共卫生, 2009, 25(10): 1235-1237. DOI: 10.11847/zgggws2009-25-10-43
引用本文: 彭仙娥, 黄之敏, 林建银, 陆青青, 林俊, 林旭. 职员非酒精性脂肪肝患病及影响因素分析[J]. 中国公共卫生, 2009, 25(10): 1235-1237. DOI: 10.11847/zgggws2009-25-10-43
PENG Xian-e, HUANG Zhi-min, LIN Jian-yin, . Prevalence and related risk factors of nonalcoholic fatty liver among administrative officials[J]. Chinese Journal of Public Health, 2009, 25(10): 1235-1237. DOI: 10.11847/zgggws2009-25-10-43
Citation: PENG Xian-e, HUANG Zhi-min, LIN Jian-yin, . Prevalence and related risk factors of nonalcoholic fatty liver among administrative officials[J]. Chinese Journal of Public Health, 2009, 25(10): 1235-1237. DOI: 10.11847/zgggws2009-25-10-43

职员非酒精性脂肪肝患病及影响因素分析

Prevalence and related risk factors of nonalcoholic fatty liver among administrative officials

  • 摘要: 目的调查福建省福州市职员非酒精性脂肪肝患病情况及其相关影响因素。方法对参加健康体检的既往无饮酒史或折合乙醇摄入量<40 g/周的3 884名职员进行调查。内容包括问卷咨询,体格检查、75 g葡萄糖耐量试验、血脂检测、以及肝脏实时超声检查。结果调整年龄性别后,非酒精性脂肪肝总患病率为27.45%,并随年龄增长而增加;男性年龄标化患病率为35.70%,高于女性的17.47%,差异有统计学意义(P<0.05);非酒精性脂肪肝者中肥胖、血脂异常、血压增高、高尿酸血症、低HDL-C血症、高LDL-C血症及血糖异常的患病率均高于非脂肪肝组,差异有统计学意义(P<0.05);多因素Logistic回归分析结果显示,性别、年龄、高甘油三酯血症、肥胖(≥25 kg/m2)、低HDL-C血症、高尿酸血症、高血糖等7项指标与非酒精性脂肪肝密切相关。结论福州市职员中非酒精性脂肪肝患病率较高,肥胖及其相关的多元代谢紊乱与脂肪肝的关系密切,应对相关危险因素进行干预。

     

    Abstract: ObjectiveTo investigate the prevalence of nonalcoholic fatty liver and its risk factors among a specific population in Fuzhou city.MethodsA total of 3 884 administrative officials who denied regular alcohol drinking participated in the survey Questionnaire survey, physical examination, serum lipid-profile, 75 gramoral glucose tolerance test and ultrasonogmphic examination of liverwere conducted.ResultsThe age-sex-adjusted prevalence of nonalcoholic fatty liver in the participants was 27.45%.The age-adjusted prevalence of nonalcoholic fatty liver in themale was 35.70% and significantly higher than that of in fem ale(17.47%,P<0.05).The prevalence of obesity, hypertension, dyslipidemia, high blood uric acid and low high-density lipoprotein cholesterol(HDL-C)in the nonalcoholic fatty liver group were significantly higher than those of in the group without fatty liver(all P<0.05).Multiple variant regression analysis showed that there were positive correlations between prevalence of nonalcoholic fatty liver and factors such as sex, age, obesity, hyperlip idemia, hypemricaemia,low HDL-C and inpaired glucose tolerance Conclusion There is a high prevalence of nonalcoholic fatty liver among administrative officials in Fuzhou.Metabolic disorders such as obesity, hyperlip idemia, and hyperuricaemis are significantly related to nonalcoholic fatty liver.

     

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