Abstract: Objective To explore epidemiologic characteristics of hospitalized patientsw ith acquired immune deficiency syndroma (ADS)/HIV infection in general hospital.Methods Them edical record of in-patients with definite diagnosis of ADS/HIV infection in the People's Hospital of Shenzhen from 1997 to Decemher,2008 were retrieved and analyzed with descriptive epidemiology.Results A total of 60 cases of ADS and 12 cases of HIV infection were retrieved.The first ADS inpatient of the hospitalwas diagnosed in 1999.There was an increase trend for the inumner of patients with ADS/HIV infection in the hospital based on Cox-stuanrt test(z=-3.532,n=5,P<0.01).Among the 60 ADS cases,34 (62.5 %)had history of visting private hospitals and 35 (64.8%)had hospitalization of 1-3 months after the occurrence of ADS symptom、Among the 12 HIV infection cases,9(75.00)were diagnosed by routine screen for HIV and 3 (25.0)were diagnosed through examination during hospitalization.The HIV screen rate at the day of hospitalization increased to 88.9% in 2008 with a 43.3% increment than before (P<0.05).Conclusion Community based health education and voluntary consultation and test free of charge should be promoted to increase diagnosis of ADS/HIV infection among high risk population.