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张玲, 华琦, 王玮, 周新, 戴颖, 王嵬. 原发性高血压患者代谢综合征发病状况分析[J]. 中国公共卫生, 2009, 25(12): 1411-1413. DOI: 10.11847/zgggws2009-25-12-02
引用本文: 张玲, 华琦, 王玮, 周新, 戴颖, 王嵬. 原发性高血压患者代谢综合征发病状况分析[J]. 中国公共卫生, 2009, 25(12): 1411-1413. DOI: 10.11847/zgggws2009-25-12-02
ZHANG Ling, HUA Qi, WANG Wei, . Incidence of metabolic syndrome in primary hypertensive and normotensive people[J]. Chinese Journal of Public Health, 2009, 25(12): 1411-1413. DOI: 10.11847/zgggws2009-25-12-02
Citation: ZHANG Ling, HUA Qi, WANG Wei, . Incidence of metabolic syndrome in primary hypertensive and normotensive people[J]. Chinese Journal of Public Health, 2009, 25(12): 1411-1413. DOI: 10.11847/zgggws2009-25-12-02

原发性高血压患者代谢综合征发病状况分析

Incidence of metabolic syndrome in primary hypertensive and normotensive people

  • 摘要: 目的 研究原发性高血压患者和血压正常者中代谢综合征(MS)患病状况及其特点.方法 随机抽选北京市宣武医院门诊体检人员429人,按原发性高血压定义分为血压正常者(134人)和原发性高血压患者(295例);应用2007年中国成人血脂异常防治指南中标准(JCDCG标准)诊断MS.结果 高血压人群的MS患病率为47.1%;其他各危险因素中,腹型肥胖和肥胖的发生率最高,分别为67.5%,64.1%;高血压合并腹型肥胖患者发生MS的风险是仅有高血压、腹型肥胖2项之一者的8.06倍(95%CI=4.76~13.64);高血压组MS、腹型肥胖、肥胖、腰臀比(WHR)异常和高胆固醇血症的发病危险分别是血压正常组的4.57,3.61,3.22,2.23和1.08倍(P<0.001);排除高血压影响以后,高血压组拥有1~4个代谢综合征危险因素的风险是血压正常组的2.83,6.86,7.59和10.29倍.结论 原发性高血压患者MS和其他各危险因素的发生率高于正常人群,合并肥胖等多种危险因素的机会更大,应重视合并有肥胖或腹型肥胖的原发性高血压患者的预防和治疗.

     

    Abstract: Objective To investigate the incidence of metabolic syndrome(MS)in primary hype rtensive and normotensive subjects.Methods Across-sectional study was conducted among 429 subjects chosen from clinical patients and divided in totwo groups as primary hype rtensive subjects(HT=295)and normo tensive subjects(NT=134).The diagnos is of MS was based on the standard definition by JCD CG.Results The inc idence of metabolic syndrome in hypertensive subjects was 47.1% and the incidence of obesity and abdominal obesity was 67.5% and 64.1%,respectively.Patients suffering from both hype rtension and abdominal obesity were 8.06(95%CI:4.76-13.64)times more likely to develop MS than patients with only one risk factor.The risks for HT group to develope MS,abdominal obesity,obesity,abnormal waist/hipratio,and dys lipidemia were 4.57,3.61,3.22,2.23,and 1.08 times of that for NT group(P<0.001).After excluding the hypertensive risk factor,HT group was 2.83,6.86,7.59,and 10.29 times likely to have 1 to 4 risk factors of MS than that for NT group.Conclusion The incidence of MS is significantly higher in hype rtensive subjects than normotensive subjects.Hypertensive subjects are more susceptible to other risk factors of MS and tend to suffer from more symptoms of MS.The intevention and treatment of hypertension,especially the prevention of hype rtension combined with obesity is of priority.

     

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