Abstract: Objective To compare the validity of "a risk model for prediction of diabetes in Chinese adults(HCI)" and "diabetes risk in Oman(Oman)" in the screening of individuals with high risk of diabetes mellitus.Methods A total of 1029 subjects aged 23 262 years were investigated with a cross-sectional study.Risk score method and WHO 1999 gold standard were adopted to screen high risk individual.Ztest was used to compare the areas under ROC(receiver operating characteristic).Results HCI and Omanrisk score of ≥1.10,>10 was used as the optimal cut-point to screen individuals at high risk,respectively.The areas under ROC were 0.82(95% confidence intervalCI:0177-0188)and 0.80 (95%CI:0.72-0.87).The sensitivity was 95%,63% and the specificity was 41%,73%,respectively.The number of individuals a thigh risk screened by HCI and Oman risk score were 6.8(60.06%)and 295(28.67%),respectively,with a poor whole agreement(Kappa=0.29).But 87.46% of the individuals at high risk screened by Oman were included by HCI,and 91.00% healthy individuals screened by HCI were also included by Oman.The Z value was 0.65(P>0.05),and the difference between two methods was not significant.Conclusion HCI and Omanrisk score both have a certa in validity,and their cut-off can distinguish individuals at high risk from healthy to some extent.The individuals at high risk screened by Oman and HCI have a good agreement.Z test shows that the validities of the two methods are not different in screening individualat high risk of diabetes.