Abstract: Objective To study malaria epidemic in Shenzhencity from 2006-2009 and to provide scientific basis for malaria control.Methods The information of blood test for three types of fever patients and active monitoring for imported malaria were summarized as well as the distribution of mosquito.Then the distribution characteristic of malaria cases and mosquito was analyzed.Results The average rate of blood test for three types of fever patients was 0.24% during 2006 to 2009.Due to the increase of importedm alaria cases, the positive rate of malaria went up obviously in 2008.Most of the malaria cases were distributed in Luohu, Longgang and Bao an district.The ratio of malignantm a laria cases was 18.91% for all cases.Vivax malaria cases were mainly distributed in worker group with high density time in June.While malignant malaria cases were mainly distributed in officer group with high density time in February and October.Imported cases found by active monitoring system were all malignant malaria.No anopheline was found in Shenzhen during the period.Conclusion The epidemic of malaria and itsmedia was properly controlled.But imported case of malignantmalaria should be considered.