Abstract: Objective To study the quality of life and its influence factors among Dai people and to provide basis for intervention measures.Methods With cluster sampling,two villages were sampled and Dai residents aged from 14 to 70 years from 185 households were selected in Xinping county,Yunnan province.Results Four domain scores and total score of quality of life among the Dai villagers were 61.3±14.2,61.1±14.1,69.4±14.5,53.1±14.5,and 56.3±21.7,respectively.The multivariate linear regression analysis results showed that the influence factors of physiological domain were education level,physical disability,chronic disease and the influence factors of Dai villagers' psychological domain were religious belief,smoking habit,height;the influence factors of social relation domain were age,marriage,education level; the influence factors of environment domain were trmiming nails,changing clothes and physical disability.Conclusion The quality of life of Dai nationality residents in Yunnan province is related to their social-economic condition and health habit.