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李健, 范岩峰, 许榕仙, 周裕林. 宫颈癌相关影响因素病例对照研究[J]. 中国公共卫生, 2011, 27(3): 264-265. DOI: 10.11847/zgggws2011-27-03-04
引用本文: 李健, 范岩峰, 许榕仙, 周裕林. 宫颈癌相关影响因素病例对照研究[J]. 中国公共卫生, 2011, 27(3): 264-265. DOI: 10.11847/zgggws2011-27-03-04
LI Jian, FAN Yan-feng, XU Rong-xian, . Relationship between cervical cancer and risk factors:a case-control study[J]. Chinese Journal of Public Health, 2011, 27(3): 264-265. DOI: 10.11847/zgggws2011-27-03-04
Citation: LI Jian, FAN Yan-feng, XU Rong-xian, . Relationship between cervical cancer and risk factors:a case-control study[J]. Chinese Journal of Public Health, 2011, 27(3): 264-265. DOI: 10.11847/zgggws2011-27-03-04

宫颈癌相关影响因素病例对照研究

Relationship between cervical cancer and risk factors:a case-control study

  • 摘要: 目的 了解宫颈癌的相关影响因素,为预防宫颈癌发病提供科学依据。方法 采用以医院为基础病例对照研究方法对2007年9月-2010年6月在福建省厦门市妇幼保健院、厦门市第一医院和厦门市中医院就诊的112例宫颈癌患者及同期就诊的200例其他疾病女性患者进行宫颈癌相关影响因素问卷调查并检测血中维生素B12及叶酸含量。结果 单因素Logistic回归分析结果表明,首次性生活年龄(OR=0.659)、首次生育年龄(OR=0.715)、叶酸含量(OR=0.386)、维生素B12含量(OR=0.661)、经常饮茶(OR=0.596)、被动吸烟(OR=1.738)、性行为时注意卫生(OR=0.483)、分娩次数(OR=1.904)是宫颈癌发病的相关影响因素;多因素Logistic回归分析结果表明,分娩次数>2次和被动吸烟是宫颈癌发病的危险因素;叶酸含量≥10 nmol/L、经常饮茶和性生活时注意卫生是宫颈癌发病的保护因素。结论 有多次分娩史和被动吸烟的妇女患宫颈癌的危险性较大;性行为时注意卫生、经常饮茶、补充叶酸可预防宫颈癌的发生。

     

    Abstract: Objective To explore the relationship bewteen the occurrence of uterine cervix cancer and risk factors.Methods Totally 112 cervical cancer patients and 200 controls were collected from three hospitals in Xiaemen city during 2007-2010.Face-to-face questionnaire survey was conducted among the subjects to get the information about cervical cancer and its related factors.Results There sults of single-factor logistic regression showed that the age at first sexual inter-course, the age of first parturition, level of folic acid and the vitam in B12, drinking tea, passive smoking, the sanitation of sexual behavior, and the times of parturition were associated with cervical cancer.The results of the multi-factor logistic regression showed that passive smoking and parturition more than twice were risk factors and paying attention to sanitation of sexual behavior, drinking tea, and with the content of folic acid more than 10nmol/L were protective factors of cervical cancer.Conclusion Passive smoking and giving birth to more children could promote the occurrence of cervical cancer and with supplement of folic acid, keeping healthy sexual behavior, and drinking tea may be the effective factors to prevent cervical cancer.

     

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