Abstract: Objective To understand the influencing factors of breast cancer screening(BCS) among women in Macao for planning health promotion strategy.Methods A cross sectional survey study of breast cancers cognition was conducted among 220 female employees in an organization and the influencing factors of BCS among the women were analyzed.Results The mean age of the employees was 44.2 years.Of all the women, 82.1% were married, 76.9% had given the birth to a child with the median of children number of 2, and 43.1% experienced breast feeding.The mean age of menophania of the women was 13.6 and 35.4% of their relatives had breast cancer history and 78.5% of them had no history of breast diseases.There was a significant difference between the women with and without experience of BCS in age(P=0 000), age of menophania (P=0.032), number of children(P=0.041), being married(P=0.000), ever given birth(P=0.000), experience of breast feeding (P=0.006), whether their relatives had breast cancer(P=0.001), and whether they had breast diseases(P=0.001).Age(odds ratioOR=1.2, P=0.000) and menses(OR=9.1, P=0.000) were contributing factors of taking BCS, but without the history of breast disease(OR=0.3, P=0.047) was a impedient factor of taking BCS.Conclusion To promote the BCS among young and menopausal women, the government should streng then the propaganda on regular BCS and health education on breast cancer.