Abstract: duates,and to provide scientific evidence for intervention.MethodsWith stratified-cluster sampling method,2 386 students in medical university were surveyed with the World Health Organization Quality of Life-Brief (WHOQOL-BREF)and QOL related factors questionnaire.ResultsThe average age of the students was 22.10±3.26 years with 1 162 males(48.7%)and 1224 females(51.3%).The scores of physiology,psychology,social relationship, environment domain,general QOL,and health status were 64.59±12.65,61.26±14.16,62.62±12.85,54.12±13.98, and 57.74±18.46,respectively.The scores of physiology domain,general QOL and health status of the students were lower than those of the norm(P<0.05).But the scores of social relationship and environment domain were higher than those of the norm(P<0.05).The score of psychology domain of the students was not significantly different from that of the norm (P>0.05).Multiple regression analysis indicated that appetite,sleep,physical exercise,alcohol drinking,gender,family income,and other factors were significant influential factors of QOL among the students.Multiple regression analysis also showed that female students,the students with good appetite,with sufficient sleep,often doing exercise,from a family of high income,without smoking and alcohol drinking,without myopic or other illness had better QOL than other students.The QOL of the students having no leadership in student organization or not attending social association,or having conflict with the family were worse than that of other students.ConclusionGender,appetite,sleep,physical exercise,family income, smoking,alcohol drinking,disease,myopia,having leadership in student or attending social association,and conflict in the family are the main influential factors of QOL among the students in medical university.