Abstract: Objective To evaluate the association between smoking and sexual function in sexually active males.Methods A total of 399 men,aged from 25 to 35 years,were surveyed on the status of smoking and sexual function using a questionnaire in an cross-sectional study.Results The proportions of lower score for sexual satisfaction,libido,erectile function,ejaculatory function,and total sexual function were 36.3%,29.9%,13.1%,14.8%,and 17.6%,respectively.In comparison with nonsmokers,the men smoked more than 10 years had a higher risk for decreased sexual desire,erectile dysfunction,and sexual dysfunction with the odds ratios(ORs) of 1.9(95% confidence intervalCI:1.2-4.3),2.1(95%CI:1.3-5.1),and 2.1(95%CI:1.2-5.3),respectively.The men smoked more than 20 cigarettes per day also had a higher risk than nonsmokers in erectile dysfunction and sexual dysfunction,with the ORs of 2.6(95% CI:1.2-5.0) and 1.9(95% CI:1.3-4.3).Conclusion Smoking can affect sexual function in sexually active males and mainly affect the libido and erectile function.