Abstract: ObjectiveTo analyze epidemiological characteristics and correlative risk factors of sequela of paralysis in 186 acute flaccid paralysis(AFP)cases and to explore relevant prevention and treatment measures.MethodsDescription epidemiological method was used to analyze the epidemiological characteristics of AFP cases with residual paralysis during 2004-2009.The correlative risk factors of sequela of paralysis were analyzed with univariate and multivariate non-conditional logistic regression.ResultsDuring the period the prevalence of sequela of paralysis in the AFP cases was 12.02%, and the prevalence in 2007-2009 decreased by 50.46% compared to that during 2004-2006.The prevalence of residual paralysis in Suqian and Xuzhou cities were higher than that of in Jiangsu province.In the 186 AFP cases,the male had a higher prevalence of residual paralysis than the female.The most of the residual paralysis cases occured between April and July and 65.59% of the residual paralysis cases were the children aged 0-4 years.The results of multivariate nonconditional logistic regression analyses showed that residual paralysis of AFP cases were associated with age,gender,history of immunization,laboratory result of stool specimen,initial paralytic degree,quality of stool specimen,and different grades of hospitals.ConclusionTo reduce the incidence of residual paralysis in AFP cases,the tow nship health institutions shouuld be bought into active monitoring system for high quality of AFP surveillance and a high immunization coverage rate and timely treatment of AFP cases should be promoted.