Abstract: Objective To investigate the knowledge about human mmunodeficiency virus/acquired immunodeficiency syndrome(HIV/AIDS)and high risk sexual behaviors among newtype drug abusers.Methods Totally 247 newtype drug abusers recruited from nine compulsory isolation detoxification centers in Liaoning province from January 2009 to December 2010 were surveyed with a questionnaire.Logistic regression analysis was used to analyze the influential factors of high risk sexual behavior among the newtype drug abusers.Results The average awareness rate of HIV/AIDS knowledge was 61.9%(153/247); the rates of non-condom use in sexual behavior and multiple sexual partners were 65.4%(140/247)and 76.5%(189/247),respectively.Multiple regression results showed that male(odds ratioOR=3.20,95% confidence intervalCI:1.34-7.63)and positive attitude to condom use(OR=3.47,95% CI:1.39-8.70)were the risk factors of high risk sexual behaviors among the newdrug abusers,whereas high AIDS knowledge score was a protective factor.Conclusion The newdrug abusers of male and with lowAIDS knowledge score and negative attitude toward condom use are more likely to have high risk sexual behaviors.