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关键词:
- 转录因子 /
- 成骨细胞 /
- Osterix(OSX)
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[24] Maehata Y,Takamiazwa S,Ozawa S,et al.Both direct and collagen-mediated signals are required for active vitamin D3-elicited differentiation of human osteoblastic cell:roles of osterix,an osteoblast-related transcription factor[J].Matrix Biol,2006,25(1):47-58. [25] Xing W,Singgih A,Kapoor A,et al.Nuclear factor-E2-related factor-1 mediates ascorbic acid induction of osterix expression via interaction with antioxidant-responsive element in bone cells[J].J Biol Chem,2007,282(30):22052-22061. [26] Lu X,Gilbert L,He X,et al.Transcriptional regulation of the osterix(OSX,Sp7) promoter by tumor necrosis factor identifies disparate effects of mitogen-activated protein kinase and NF kappa B pathways[J].J Biol Chem,2006,281(10):6297-6306. [27] Zambetti GP,Horwitz EM,Schipani E.Skeletons in the p53 tumor suppressor closet:genetic evidence that p53 blocks bone differentiation and development[J].J Biol,2006,172(6):795-797. 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