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内皮型一氧化氮合酶基因多态性与心血管疾病关系

邹放君 邓峰美

邹放君, 邓峰美. 内皮型一氧化氮合酶基因多态性与心血管疾病关系[J]. 中国公共卫生, 2013, 29(2): 299-302. doi: 10.11847/zgggws2013-29-02-49
引用本文: 邹放君, 邓峰美. 内皮型一氧化氮合酶基因多态性与心血管疾病关系[J]. 中国公共卫生, 2013, 29(2): 299-302. doi: 10.11847/zgggws2013-29-02-49

内皮型一氧化氮合酶基因多态性与心血管疾病关系

doi: 10.11847/zgggws2013-29-02-49
基金项目: 

国家自然科学基金(30860102)

详细信息
    作者简介:

    邹放君(1979- ),男,湖南衡阳人,硕士在读,研究方向:心血管疾病。

    通信作者:

    邓峰美,E-mail:dengfengmei@yahoo.com.cn

  • 中图分类号: R181.3

  • [1] Tsukada T,Yokoyam K,Arai T,et al.Evidence of association of the eNOS gene polymorphism with plasma NO metabolite levels in humans[J].Biochem Biophys Res Commun,1998,245(1):190-193.
    [2] Yoshimura M,Yasue H,Nakayama M,et al.A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is associated with coronary spasm in the Japanese[J].Hum Genet,1998,103(1):65-69.
    [3] Miyamoto Y,Saito Y,Nakayama M,et al.Replication protein AI reduces transcription of the endothelial nitric oxide synthase gene containing a 786TC mutation associated with coronary spastic angina[J].Hum Mol Genet,2000,9(18):2629-2637.
    [4] Uwabo J,Soma M,Nakayama T,et al.Association of a variable number of tandem repeat in the endothelial constitutive nitric oxide synthase gene with essential hypertension in Japanese[J].Am J Hypertens,1998,11(1):125-128.
    [5] Rodrguez-Esparragn FJ,Rodrguez-Prez JC,Macas-Reyes A,et al.Peroxisome proliferator-activated receptor-[gamma]2 Pro12Ala and endothelial nitric oxide synthase-4a/b gene polymorphisms are associated with essential hypertension[J].J Hypertens,2003,21(9):1649-1655.
    [6] Moe KT,Lim ST,Wong P,et al.Association analysis of endothelial nitric oxide synthase gene polymorphism with primary hypertension in a Singapore population[J].Journal of Human Hypertension,2006,20(12):956-963.
    [7] Jemaa R,Ben Ali S,Kallel A,et al.Association of a 27-bp repeat polymorphism in intron 4 of endothelial constitutive nitric oxide synthase gene with hypertension in a Tunisian population[J].Clin Biochem,2009,42(9):852-856.
    [8] 伍小锋,黄汉涛,黄青阳,等.eNOS基因多态性与湖北汉族人群原发性高血压相关[J].中华内分泌代谢杂志,2005,25(5):522-523.
    [9] Miyamoto Y,Saito Y,Kajiyama N,et al.Endothelial nitric oxide synthase gene is positively associated with essential hypertension[J].Hypertension,1998,32(1):3-8.
    [10] Olcay A,Ekmekci CG,Ozbek U,et al.Negative association of endothelial nitric oxide gene polymorphism with hypertension in Turkish patients:effect of ecNOS polymorphism on left ventricular hypertrophy[J].Cardiovasc Ultrasound,2006,4:33-38.
    [11] Deng F,Hu Q,Tang B,et al.Endothelial nitric oxide synthase gene intron 4,27 bp repeat polymorphism and essential hypertension in the Kazakh Chinese population[J].Acta Biochim Biophys Sin(Shanghai),2007,39(5):311-316.
    [12] Lacolley P,Gautier S,Poirier O,et al.Nitric oxide synthase gene polymorphisms,blood pressure and aortic stiffness in normotensive and hypertensive subjects[J].J Hypertens,1998,16(1):31-35.
    [13] Veldman BA,Spiering W,Doevendans PA,et al.The Glu298Asp polymorphism of the NOS3 gene as a determinant of the baseline production of nitric oxide[J].J Hypertens,2002,20(10):2023-2027.
    [14] Wang CJ,Zhao JB,Xu JL,et al.Meta-analysis on the association of G894T polymorphism in endothelial nitric oxide synthase gene and essential hypertension in Chinese population[J].Zhong-hua Liu Xing Bing Xue Za Zhi,2009,30(8):845-849.
    [15] Tang W,Yang Y,Wang B,et al.Association between a G894T polymorphism of eNOS gene and essential hypertension in Hani and Yi minority groups of China[J].Archives of Medical Research,2008,39(1):222-225.
    [16] Periaswamy R,Gurusamy U,Shewade DG,et al.Gender specific association of endothelial nitric oxide synthase gene(Glu298Asp)polymorphism with essential hypertension in a south Indian population[J].Clin Chim Acta,2008,395(1-2):134-136.
    [17] Kato N,Sugiyama T,Morita H,et al.Lack of evidence for association between the endothelial nitric oxide synthase gene and hypertension[J].Hypertension,1999,33(4):933-936.
    [18] Woff B,Grabe HJ,Schluter C,et al.Endothelial nitric oxide synthase Glu298Asp gene polymorphism,blood pressure and hypertension in a general population sample[J].Hyporterm,2005,23(7):1361-1366.
    [19] Khawaja MR,Taj F,Ahmad U,et al.Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population[J].Int J Cardiol,2007,116(1):113-115.
    [20] Hyndman ME,Parsons HG,Verma S,et al.The T-786--C mutation in endothelial nitric oxide synthase is associated with hypertension[J].Hypertension,2002,39(4):919-922.
    [21] 李东宝,华琦,皮林.内皮型一氧化氮合酶基因T786C 多态性与原发性高血压的相关关系[J].首都医科大学学报,2006,27(2):226-229.
    [22] Nejatizadeh A,Kumar R,Stobdan T,et al.Endothelial nitric oxide synthase gene haplotypes and circulating nitric oxide levels significantly associate with risk of essential hypertension[J].Free Radic Biol Med,2008,44(11):1912-1918.
    [23] Tsujita Y,Baba S,Yamauchi R,et al.Association analyses between genetic polymorphisms of endothelial nitric oxide synthase gene and hypertension in Japanese:the Suita Study[J].J Hypertens,2001,19(11):1941-1948.
    [24] Zhao Qi,Su SY,CHEN SF,et al.Association study of the endothelial nitric oxide synthase gene polymorphisms with essential hypertension in northern Han Chinese[J].Chinese Medical Journal,2006,119(13):1065-1071.
    [25] Fatini C,Sofi F,Sticchi E,et al.Influence of endothelial nitric oxide synthase gene polymorphisms(G894T,4a4b,T-786C)and hyperhomocysteinemia on the predisposition to acute coronary syndromes[J].Am Heart J,2004,147(3):516-521.
    [26] 胡茂红,贾崇奇,刘同涛,等.内皮型一氧化氮合酶基因多态性与冠心病关系[J].中国公共卫生,2007,23(1):58-60.
    [27] Vasilakou M,Votteas V,Kasparian C,et al.Lack of association between endothelial nitric oxide synthase gene polymorphisms and risk of premature coronary artery disease in the Greek population[J].Acta Cardiol,2008,63(5):609-614.
    [28] Hibi K,Ishigami T,Tamura K,et al.Endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction[J].Hypertension,1998,32(3):521-526.
    [29] Colombo MG,Andreassi MG,Paradossi U,et al.Evidence for association of a common variant of the endothelial nitric oxide synthase gene(Glu298Asp polymorphism)to the presence,extent,and severity of coronary artery disease[J].Heart,2002,87(6):525-528.
    [30] Gardemann A,Lohre J,Cayci S,et al.The T allele of the missense associated with coronary heart disease in younger individuals with high atherosclerotic risk profile[J].Atherosclerosis,2002,160(1):167-175.
    [31] Salimi S,Firoozrai M,Zand H,et al.Endothelial nitric oxide synthase gene Glu298Asp polymorphism in patients with coronary artery disease[J].Ann Saudi Med,2010,30(1):33-37.
    [32] Motawi T,Shaker O,Taha M,et al.Endothelial nitric oxide synthase and angiotensinogen gene polymorphism in coronary artery diseases in Egypt[J].Angiology,2011,62(2):191-197.
    [33] Wang CL,Hsu LA,Ko YS,et al.Lack of association between the Glu298Asp variant of the endothelial nitric oxide synthase gene and the risk of coronary artery disease among Taiwanese[J].J Formos Med Assoc,2001,100(11):736-740.
    [34] Aras O,Hanson NQ,Bakanay SM,et al.Endothelial nitric oxide gene polymorphism(Glu298Asp)is not associated with coronary artery disease in Turkish population[J].Thromb Haemost,2002,87(2):347-349.
    [35] Nakayama M,Yasue H,Yoshimura M,et al.T786C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with myocardial infarction,especially without coronary organic stenosis[J].AmJ Cardiol,2000,86(6):628-634.
    [36] Colombo MG,Paradossi U,Andreassi MG,et al.Endothelial nitric oxide synthase gene polymorphisms and risk of coronary artery disease[J].Clin Chem,2003,49(3):389-395.
    [37] Alkharfy KM,Al-Daghri NM,Al-Attas OS,et al Endothelial nitric oxide synthase gene polymorphisms(894GT and-786TC)and risk of coronary artery disease in a Saudi population[J].Arch Med Res,2010,41(2):134-141.
    [38] 李敏,贾崇奇,刘同涛,等.eNOS基因T-786C变异与早发冠心病关系[J].中国公共卫生,2007,23(5):583-585.
    [39] Alp E,Menevse S,Tulmac M,et al.Lack of association between matrix metalloproteinase-9 and endothelial nitric oxide synthase gene polymorphisms and coronary artery disease in Turkish population[J].DNA Cell Biol,2009,28(7):343-350.
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出版历程
  • 接收日期:  2012-01-16
  • 刊出日期:  2013-02-10

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