Abstract: ObjectiveTo explore the association of cognitive emotion regulation strategy and depression among nurses and to provide evidence for enhancing the ability of emotional regulation in nurses. MethodsA total of 280 nurses from two general hospitals of grade three-class one were tested with Cognitive Emotion Regulation Questionnaire(CERQ) and Self-Rating Depression Scale (SDS). ResultsAmong the nurses the average score of positive cognitive emotion regulation strategy was significantly higher than that of negative cognitive emotion regulation strategy (12.91±2.75 vs 11.32±2.18,t=3.011;P<0.05).The nurses with higher professional titles were more likely to use positive strategies while the nurses with lower titles were more likely to use negative strategies.Compared with the national norm,the depression score of the nurses was significantly higher(P<0.01) and the depression score of the nurses was inversely correlated with their professional titles.Negative cognitive regulation strategies (self-blame,catasrophizing,other-blame) were positively correlated with depression and positive cognitive regulation strategies (acceptance,positive refocusing,reasonable analysis were inversely correlated with depression among the nurese. ConclusionThere is a close relationship between cognitive emotion regulation strategies and professional titles among nurses and both positive and negative cognitive emotion regulation strategies have significant impact on depression status among nurses.