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杨铮, 陆金根, 花永强, 尤圣富, 万崇华, 郑培永, 宋毅, 柳涛. 基于中医理论胃癌生活质量评价量表研制[J]. 中国公共卫生, 2013, 29(7): 960-964. DOI: 10.11847/zgggws2013-29-07-07
引用本文: 杨铮, 陆金根, 花永强, 尤圣富, 万崇华, 郑培永, 宋毅, 柳涛. 基于中医理论胃癌生活质量评价量表研制[J]. 中国公共卫生, 2013, 29(7): 960-964. DOI: 10.11847/zgggws2013-29-07-07
YANG Zheng, LU Jin-gen, HUA Yong-qiang.et al, . Development of quality of life assessment instrument for gastric cancer patients (QLASTCM-Ga) based on traditional Chinese medicine[J]. Chinese Journal of Public Health, 2013, 29(7): 960-964. DOI: 10.11847/zgggws2013-29-07-07
Citation: YANG Zheng, LU Jin-gen, HUA Yong-qiang.et al, . Development of quality of life assessment instrument for gastric cancer patients (QLASTCM-Ga) based on traditional Chinese medicine[J]. Chinese Journal of Public Health, 2013, 29(7): 960-964. DOI: 10.11847/zgggws2013-29-07-07

基于中医理论胃癌生活质量评价量表研制

Development of quality of life assessment instrument for gastric cancer patients (QLASTCM-Ga) based on traditional Chinese medicine

  • 摘要: 目的研制基于中医理论的恶性肿瘤生活质量评价体系之胃癌量表QLASTCM-Ga并对其测量学特性进行评价。方法采用程序化决策方式(议题小组和核心小组)和量表开发理论分别研制共性模块与特异模块,二者结合形成量表,并通过240例胃癌患者生命质量测定对量表的测量学特性(信度、效度、反应度)进行评价,采用相关分析、因子分析及配对t检验等进行统计分析。结果 该量表及各领域的重测信度在为0.90~0.94间,各领域内部一致性α值为0.86~0.93;相关分析与因子分析显示较好的结构效度;与QLQ-STO 52为效标的效标关联效度较好;已知组比较显示较好的临床效度;治疗后各领域及总量表得分均有统计学意义,且标准化反应均数SRM与QLQ-STO 52接近。结论 QLASTCM-Ga具有较好的信度、效度及一定的反应度,可用于胃癌患者的生命质量测定。

     

    Abstract: Objective To develop a quality of life assessment scale for gasric cancer patients (QLASTCM-Ga) based on traditional Chinese medicine and to evalucte its psychometric property.Methods The structured group method (nominal group and focus group) and the theory in developing rating scale were employed to establish the general and the specific module,respectively.The full instrument was formed by combination of two modules and psychometric properties (reliability,validity,and responsiveness) were evaluated by quality of life (QOL) data measured in 240 gastric cancer patients.Statistical methods used were correlation analysis,factor analysis and paired t test.Results Test-retest reliability of the overall scale and all domains were from 0.90 to 0.94,and internal consistency α were from 0.86 to 0.93.Correlation and factor analyses demonstrated that the scale was good in construct validity and known-group comparisons displayed a good clinical validity of the scale.Criterion-related validity was confirmed.wtih European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire-Stomach Cancer (QLQ-STO 52) as the criterion.Statistically significant changes were found for each domain and the overall scale,with the standardized response means (SRMs) being close to those of QLQ-STO 52.Conclusion The QLASTCM-Ga could be used to measure QOL for patients with gastric cancer with good validity,reliability,and reasonable responsiveness.

     

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