Abstract: Objective To detect the residues of quinolones(ofloxacin,ciprofloxacin,enrofloxacin) in meat products commercially available in Ji'nan,Shandong province and to provide relevant information to ensure food safety.Methods A total of 270 samples were collected randomly from 10 areas in 5 administrative districts of Ji'nan city and quinolenes residues in the samples were analyzed with high performance liquid chromatography (HPLC).The measurement Results were assessed according to Maximum Residue Levels(MRLs) of Veterinary Drugs in Animal Foods.Results For the 270 samples,the quinolones detection rate was 28.15% and the exceeding standard rate was 24.44%,with a concentration range from 21.61 to 15 134.75 μg/kg.The exceeding standard rates of quinolones for pig kidneys and livers were 43.33% and 27.50%,which were higher than that for pork(13.33%)(P<0.05).The exceeding standard rate for chicken gizzards was 35.29%,which was higher than that for liver(28.13%) and chicken meat(9.76%)(P<0.05).The exceeding standard rate in beef was 27.50% and no residue was detected in mutton.The exceeding standard rates for samples from supermarkets and farmer's markets were 27.34% and 21.83%,without significant difference(P>0.05).The exceeding standard rate for non-brand meat was 24.82% and 24.06% for brand meat,without significant difference(P>0.05).Conclusion There are different levels of quinolones residues in meat products sold in Ji'nan city.