Abstract: ObjectiveTo investigate the subjective well-being (SWB) and its influencing factors among clinical nurses and to provide reference for mental health promotion in nursing staff.MethodsA General Information Questionnaire,the Campbell Subjective Well-Being Scale,Perceived Social Support Scale,General Self-Efficacy Scale,the Self-Esteem Scale,Simplified Coping Style Questionnaire,and Revised Life Orientation Test were adopted to collect information in 291 on-the-job nurses.ResultsThe average score was 10.75±1.94 for overall SWB,65.55±9.86 for social support,2.50±0.53 for self-efficacy,19.71±3.48 for self-esteem,2.00±0.40 for positive coping,1.20±0.50 for negative coping,and 15.01±3.37 for optimistic tendency,respectively.The self-assessment of health,monthly income,social support,positive coping,optimistic tendency,self-esteem,and self-efficacy had significant positive correlations with SWB (P<0.05 or P<0.01).In regression analyses,variables of social support,self-assessment of health,optimistic tendency,positive coping,and monthly income entered the regression equation,and could explain 32.7% of the total SWB score.ConclusionThis study suggests that the SWB of clinical nurses is at a good level and social support,self-assessment of health,optimistic tendency,positive coping,and monthly income are significant influencing factors of SWB in the nurses.