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邓兰云. 子宫肌瘤发病危险因素分析[J]. 中国公共卫生, 2014, 30(6): 807-808. DOI: 10.11847/zgggws2014-30-06-38
引用本文: 邓兰云. 子宫肌瘤发病危险因素分析[J]. 中国公共卫生, 2014, 30(6): 807-808. DOI: 10.11847/zgggws2014-30-06-38
DENG Lan-yun. Risk factors of uterine leiomyoma among married women:a case-control study[J]. Chinese Journal of Public Health, 2014, 30(6): 807-808. DOI: 10.11847/zgggws2014-30-06-38
Citation: DENG Lan-yun. Risk factors of uterine leiomyoma among married women:a case-control study[J]. Chinese Journal of Public Health, 2014, 30(6): 807-808. DOI: 10.11847/zgggws2014-30-06-38

子宫肌瘤发病危险因素分析

Risk factors of uterine leiomyoma among married women:a case-control study

  • 摘要: 目的了解已婚女性子宫肌瘤患病相关危险因素,为制订有效防治策略提供依据。方法采用1∶1配对病例研究方法,对300例子宫肌瘤患者及300例均衡条件相等的健康人群进行问卷调查,分析子宫肌瘤发病的相关因素。结果单因素分析结果显示,宫颈糜烂(OR=10.414)、盆腔炎(OR=5.205)、月经失调(OR=6.167)、附件炎(OR=12.000)、家庭妇科肿瘤史(OR=4.142)及人均收入低(OR=2.779)是子宫肌瘤发病的危险因素;多因素logisic回归分析结果显示,宫颈糜烂(OR=9.36,95%CI=3.766~28.549)、盆腔炎(OR=5.165,95%CI=1.731~17.503)、月经失调(OR=7.791,95%CI=2.431~27.245)、家庭妇科肿瘤史(OR=3.991,95%=1.239~13.678)为子宫肌瘤发生的主要危险因素。结论子宫肌瘤发生与女性生殖系统长期炎症浸润、宫颈炎、盆腔炎、妇科疾病及家族妇科肿瘤病史有关。

     

    Abstract: ObjectiveTo explore risk factors of uterine leiomyoma among married women and to provide a basis for making preventive strategies for the disease.MethodsA questionnaire survey was conducted among 300 married women diagnosed with uterine leiomyoma selected from outpatients or physical examinees and 300 age-and marital status-matched healthy women.Logistic regression was adopted in data analyses.ResultsUnivariate analyses demonstrated that cervical erosion(odds ratio OR=10.414),pelvic inflammation(OR=5.205),emmeniopathy(OR=6.167),adnexitis(OR=12.000),familial history of gynecological tumor(OR=4.142),and low average individual income(OR=2.779)were risk factors of uterine leiomyoma;the results of multivariate logistic regression revealed that cervical erosion(OR=9.36,95% confidence interval 95% CI:3.766-28.549),pelvic inflammation(OR=5.165,95% CI:1.731-17.503),emmeniopathy(OR=7.791,95% CI:2.431-27.245),and familial history of gynecological tumor(OR=3.991,95% CI:1.239-13.678)were major risk factors of uterine leiomyoma.ConclusionThe incidence of uterine leiomyoma is related to cervical and pelvic inflammation,gynecological diseases and familial history of gynecologica tumor and regular screening on gynecological diseases is warranted for the control of uterine leiomyoma among married women.

     

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