Abstract: Objective To examine the prevalence of diarrhea symptom among diagnosed brucellosis patients in acute period and to explore the causes of diarrhea in the patients.Methods Totally 311 acute brucellosis patients were recruited in Liaoning province and routine stool examination and pathogen isolation of stool samples were conducted in the patients.Experimental treatment was carried out for the patients based on the results of laboratory detection.Results Of all the patients, only one had acute diarrhea;the patient was positive for Brucella antibody but negative for Brucella isolation and had abnormal red blood cell count(RBC)and white blood cell count(WBC)and positive result for Salmonella isolation of stool sample.The case was cured after specific treatment for Salmonella enteritis.Conclusion Brucella infection does not induce diarrhea in brucellosis patients and enteritis caused by other diarrheal pathogens may be the cause of complicated diarrhea among patients with acute brucellosis reported by researchers.