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杜楠, 彭浩, 张秋, 晁湘琴, 田洪刚, 佟伟军, 李红美. 苏州市30岁人群尿微量白蛋白异常与肥胖关系[J]. 中国公共卫生, 2015, 31(1): 42-45. DOI: 10.11847/zgggws2015-31-01-13
引用本文: 杜楠, 彭浩, 张秋, 晁湘琴, 田洪刚, 佟伟军, 李红美. 苏州市30岁人群尿微量白蛋白异常与肥胖关系[J]. 中国公共卫生, 2015, 31(1): 42-45. DOI: 10.11847/zgggws2015-31-01-13
DU Nan, PENG Hao, ZHANG Qiu.et al, . Association between abnormal urinary microalbumin and obesity among adults in Suzhou city[J]. Chinese Journal of Public Health, 2015, 31(1): 42-45. DOI: 10.11847/zgggws2015-31-01-13
Citation: DU Nan, PENG Hao, ZHANG Qiu.et al, . Association between abnormal urinary microalbumin and obesity among adults in Suzhou city[J]. Chinese Journal of Public Health, 2015, 31(1): 42-45. DOI: 10.11847/zgggws2015-31-01-13

苏州市30岁人群尿微量白蛋白异常与肥胖关系

Association between abnormal urinary microalbumin and obesity among adults in Suzhou city

  • 摘要: 目的 探讨江苏省苏州市≥30岁人群尿微量白蛋白异常与肥胖的关系,为采取相应的干预措施提供参考依据。方法 采取多阶段整群随机抽样方法对在苏州市金阊区8个小区抽取的2 889名≥30岁常住居民进行问卷调查、体格检查和实验室检测,并采用logistic回归模型分析尿微量白蛋白异常与肥胖的关联性。结果 苏州市调查的2 889名≥30岁人群中,尿微量白蛋白异常者446例,检出率为15.44%;尿微量白蛋白异常组与正常组人群比较,体质指数(BMI:25.3 vs 24.4)、腰围(WC:84.0 vs 82.0)、腰臀比(WHR:0.88 vs 0.87)的水平均高于正常组(P<0.01),以这3个指标定义的肥胖和中心性肥胖率均高于正常组(P<0.001);在调整性别、年龄、文化程度、婚姻状况、吸烟、饮酒、血糖、收缩压、舒张压、总胆固醇、甘油三酯、血清尿酸等因素后,多因素logistic回归分析结果显示,BMI肥胖者(OR=1.610,95%CI=1.189~2.181)和WHR中心性肥胖者(OR=1.349,95%CI=1.078~1.688)均可增加≥30岁人群尿微量白蛋白异常的危险性;当BMI肥胖和WHR中心性肥胖者同时存在时,≥30岁人群尿微量白蛋白异常的危险性为无BMI肥胖和WHR中心性肥胖者的1.937倍(OR=1.937,95%CI=1.370~2.740)。结论 肥胖是尿微量白蛋白异常的危险因素。

     

    Abstract: Objective To investigate the association between abnormal urinary microalbumin and indexes of obesity among adults.Methods Using multistage cluster random sampling,2 889 permanent residents aged 30 years and older were selected from 8 communities in Jichang district of Suzhou city for a questionnaire surrey and physical examination.Height,weight,blood pressure,waist and hip circumference(WC)were measured and and information on cigarette smoking,alcohol intake,and salt consumption were collected.Serum uric acid,urinary albumin,urinary creatinine,total cholesterol,and triglyceride were tested among the residents.Association between the elevated level of urinary microalbumin and the indexes of obesity was analyzed by using logistic regression model.Results The mean levels of body mass index(BMI),WC,and waist to hip ratio(WHR)in the group with elevated urinary microalbumin were higher than those in the normal group(BMI:25.3 vs. 24.4,WC:84.0 vs. 82.0,WHR:0.88 vs. 0.87).The prevalence of obesity defined according to BMI,WC and WHR showed significant differences between the two groups of different microalbumin(P<0.05).After multivariable adjustment,the elevated BMI and WHR levels also increased the risk of higher urinary microalbumin,with the odds ratios(ORs)of 1.610 and 1.349,respectively.Compared to normal BMI and WHR groups,the group with both higher WHR and BMI had a higher risk of elevated urinary microalbumin,with the OR of 1.937(95% confidence interval:1.370-2.740).Conclusion Obesity is a risk factor for elevated urinary microalbumin among adults.

     

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