Abstract: ObjectiveTo examine the prevalence of osteoporosis and its influencing factors among the residents in Wuxi city for making efficient measures and policies to prevent the disease.MethodsA total of 65 016 community residents aged≥18 years were selected with stratified cluster random sampling and investigated with a questionnaire on health status and chronic disease in Wuxi city.SPSS software was used in data analyses.ResultsThe results of multivariate logistic regression analyses showed that the prevalence of osteoporosis in the residents was associated with gender(with the odds ratioORof 2.13 for the female compared to the male),age(with the ORs of 5.13,10.99,14.02,18.83,and 18.87 for the of residents aged 50-59,60-69,70-79,80-89 and ≥90 years compared to those of aged less than 20 years),occupation(with the OR of 1.35 for office workers compared with governmental or organizational staff and enterprise managers),sleep quality( with the ORs of 1.21 and 1.39 for the residents with general and poor quality sleep compared to those with good quality sleep quality),daily life stress(with the ORs of 1.33 and 1.45 for the residents having moderate and severe daily life stress compared to those having no daily life stress),and occupational physical labor( with the ORs of 1.14 and 1.32 for the residents having light and moderate occupational physical labor compared with those having occupational physical labor seldomly);the results also revealed that the risk factors included high waist circumstance(OR=1.14),high body mass index(OR=1.32),alcohol drinking(OR=1.02),vigorous physical exercise(OR=1.20 for having physical exercise 6 times a week or more compared to less than 1 time a week),consuming less amount of vegetables(OR=1.35 and 1.84 for consuming vegetables<0.25 kg and>0.25 kg but<0.5 kg compared to consuming vegetables>0.5 kg),diabetes(OR=1.20),chronic nephritis(OR=3.54),chronic hepatitis(OR=4.41),and hyperthyroidism(OR=4.25)and the protective factors included light to moderate physical exercise(OR=0.79 and 0.83 for the physical exercise of 1-2 and 3-5 times/week compared to<1 time/week).ConclusionHaving healthy life style,light or moderate physical exercise,and decreasing daily life stress are helpful to the prevention of osteoporosis among community residents in Wuxi city.