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张云权, 吴凯, 朱慈华, 邓芷晴, 谭晓东, 马露. 武汉大气污染与缺血性心脏病死亡关系季节差异[J]. 中国公共卫生, 2015, 31(7): 926-929. DOI: 10.11847/zgggws2015-31-07-19
引用本文: 张云权, 吴凯, 朱慈华, 邓芷晴, 谭晓东, 马露. 武汉大气污染与缺血性心脏病死亡关系季节差异[J]. 中国公共卫生, 2015, 31(7): 926-929. DOI: 10.11847/zgggws2015-31-07-19
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ZHANG Yun-quan, WU Kai, ZHU Ci-hua.et al, . Seasonal variation in association between air pollution and ischemic heart disease mortality in Wuhan,China[J]. Chinese Journal of Public Health, 2015, 31(7): 926-929. DOI: 10.11847/zgggws2015-31-07-19
Citation: ZHANG Yun-quan, WU Kai, ZHU Ci-hua.et al, . Seasonal variation in association between air pollution and ischemic heart disease mortality in Wuhan,China[J]. Chinese Journal of Public Health, 2015, 31(7): 926-929. DOI: 10.11847/zgggws2015-31-07-19
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武汉大气污染与缺血性心脏病死亡关系季节差异

Seasonal variation in association between air pollution and ischemic heart disease mortality in Wuhan,China

    摘要
  • 摘要: 目的 评价大气污染物的短期暴露对居民缺血性心脏病(IHD)死亡的影响及其影响的季节差异。方法 收集湖北省武汉市江岸区2002年1月1日—2010年12月31日IHD死亡监测资料和同期环境监测中心大气污染物浓度数据,应用基于广义相加模型的时间序列分析方法,分别构建全季节模型和分季节模型,定量评价大气污染对居民IHD死亡的影响。结果 4个季节中,大气污染水平和IHD死亡人数均在冬季达到最高,冬季可吸入颗粒物PM10、SO2和NO2年均浓度分别为(143.8±70.9)、(71.0±42.4)和(66.5±25.6)μg/m3,IHD日均死亡1.64人。全季节模型中,1 d滞后(Lag1)的PM10浓度每升高10 μg/m3,IHD死亡率增加0.86%(95%CI= 0.22%~1.51%),其他气态污染物SO2、NO2与全季节IHD死亡无统计学关联;分季节建模后,PM10、SO2和NO2对IHD死亡的影响均出现在冬季,其他季节的影响均无统计学意义;其中,1 d滞后的PM10、SO2和NO2 浓度每升高10 μg/m3,冬季IHD死亡率分别增加1.40%(95%CI=0.58%~2.23%)、1.65%(95%CI=0.28%~3.05%)和3.05%(95%CI=0.92%~5.23%)。结论 武汉市大气污染的短期暴露会引起IHD死亡风险增加,且大气污染对IHD死亡的作用效应呈现一定的季节差异,冬季的影响表现更为明显。

     

    Abstract: Objective To explore the association between short-term exposure to ambient air pollution and ischemic heart disease(IHD)mortality as well as seasonal variation of the association in Wuhan city,China.Methods Data on daily IHD mortality for the period of 2002 through 2010 was obtained from Jiang'an District Center for Disease Control and Prevention,Wuhan and the data on concentration of relevant air pollution and meteorological factors from local municipal environmental monitoring center and meteorology bureau of Wuhan,respectively.Quasi-Poisson regression of generalized additive model was applied to evaluate the association between air pollution and IHD mortality,using both all-season and season-specific models.Results Ambient pollution level and IHD deaths reached highest in winter among the four seasons.Annual average concentrations of particulate matter less than 10 μm in aerodynamic diameter(PM10),sulfur dioxide(SO2),and nitrogen dioxide(NO2)in winter were 143.8±70.9 μg/m3,71.0±42.4 μg/m3,and 66.5±25.6 μg/m3,respectively,and 1.64 IHD deaths per day occurred in winter.In all-season model,a 10 μg/m3 increase in previous day(lag 1)for PM10 was associated with 0.86%(95%confidence interval95%CI:0.22%-1.51%)excess risk in IHD mortality and no statistically significant association between gaseous pollutants(SO2,NO2)and IHD mortality was found.The season-specific model showed that ambient pollutants were consistently associated with increased IHD mortality only in winter(from 1st of November to 28th of February)and a 10 μg/m3 increase in previous day(lag1)ambient pollutants was associated with 1.40%(95%CI:0.58%-2.23%)excess risk in IHD mortality for PM10,1.65%(95%CI:0.28%-3.05%)excess risk for SO2,and 3.05%(95%CI:0.92%-5.23%)excess risk for NO2,respectively.Conclusion In Wuhan city,short-term exposure to air pollution was associated with increased IHD death and a seasonal pattern with an obvious peak in winter was consistently found in the acute effects of both PM10 and gaseous pollutants(SO2,NO2)on IHD mortality.

     

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