Abstract: ObjectiveTo analyze the awareness rate of immunization-related knowledge before and after the implementation of ‘mom classroom’-a training program among parents of infants and to explore new patterns for health education on immunization.MethodsTotally 4 420 parents visiting 47 vaccination clinics for the first immunization schedule registration of their infants were recruited for a training program on vaccination,namely ‘mom classroom’,and surveyed with a questionnaire on vaccination related knowledge before and after the training from July to December,2014.ResultsAmong the participants,the awareness rate of Expanded Programme on Immunization(EPI) were 70.4% and 85.3% and there were significant differences in the awareness rates of 9 items of EPI before and after the training(all P<0.01).There were significant differences in the awareness rate of EPI among the participants with different living places(71.1% for suburban area and 69.1% for urban area),household registration status(71.5% for the migrants and 69.3% for the permanent residents),education level(69.6% for primary school,71.8% for junior high school,70.9% for senior high school,and 70.0% for college or above),and whether having knowledge about vaccination procedures(72.9% for those answering ‘yes' and 69.1% for ‘no') before the training(all P<0.05),while there was only a difference in the rate among the participants with different education level(80.8% for primary school,84.4% for junior high school,86.1% for senior high school,and 86.1% for college or above) after the training(P<0.01).ConclusionAs a new model of health education,‘mom classroom’ program could improve the awareness of knowledge about EPI among the parents of infants and promote the initiative for their babies' vaccination.