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李越, 丁李路, 边学峰, 孙强. 社区综合干预对重性精神病患者复发率影响[J]. 中国公共卫生, 2016, 32(3): 398-401. DOI: 10.11847/zgggws2016-32-03-40
引用本文: 李越, 丁李路, 边学峰, 孙强. 社区综合干预对重性精神病患者复发率影响[J]. 中国公共卫生, 2016, 32(3): 398-401. DOI: 10.11847/zgggws2016-32-03-40
LI Yue, DING Li-lu, BIAN Xue-feng.et al, . Effect of comprehensive community intervention on recurrence rate of severe mental patients in China:a meta-analysis[J]. Chinese Journal of Public Health, 2016, 32(3): 398-401. DOI: 10.11847/zgggws2016-32-03-40
Citation: LI Yue, DING Li-lu, BIAN Xue-feng.et al, . Effect of comprehensive community intervention on recurrence rate of severe mental patients in China:a meta-analysis[J]. Chinese Journal of Public Health, 2016, 32(3): 398-401. DOI: 10.11847/zgggws2016-32-03-40

社区综合干预对重性精神病患者复发率影响

Effect of comprehensive community intervention on recurrence rate of severe mental patients in China:a meta-analysis

  • 摘要: 目的 定量评估社区综合干预对重性精神病患者复发率的影响。方法 以重性精神病、精神分裂症、社区(severe mental disease,severe psychosis,schizophrenia,community,China)为检索关键词,检索中国学术文献总库(CNKI)、数字化期刊全文数据库(万方)、中文科技期刊数据库(VIP)、中国生物医学文献数据库和外文数据库Pubmed、Elsevier Science Direct、web of knowledge,收集2004年以来发表的社区干预对重性精神病患者复发率影响的随机对照试验(RCT)和非随机对照同期试验(NRCCT)研究,以Stata 12软件进行meta分析。结果 最终纳入中文文献9篇、英文文献1篇,累计干预组人数854例,对照组人数832例;meta分析结果显示,采取社区综合干预组的重性精神病患者在随访期间复发的危险度是对照组的0.322倍(OR=0.322,95% CI=0.241~0.430);漏斗图未观察到显著的不对称性,以0.1为检验水准进行Begger检验和Egger检验,P=0.283和0.151,均>0.1,未观察到本次meta分析受发表偏倚的影响,敏感性分析表明结果较为稳健。结论 社区综合干预能有效预防重性精神病的复发,是提高精神卫生服务可及性以及减轻重性精神病患者对家庭和社会负担的有效措施。

     

    Abstract: Objective To evaluate the effect of comprehensive community management on recurrence rate of severe mental patients.Methods A comprehensive search was performed through databases including PubMed, Elsevier Science Direct, Web of Knowledge, China Knowledge Infrastructure(CNKI), China Online Journals, Chinese Science and Technology Periodical Database, and Chinese Biomedical Database using the key words including severe mental disease, severe psychosis, schizophrenia, community, and China to identify completely randomized controlled trials and non-randomized concurrent controlled trials of community-based rehabilitation intervention on severe mental patients from April 2004 through April 2015.Stata 12 software was adopted for meta-analysis.Results Ten articles(nine published in Chinese and one in English) were included, with totally 854 intervened cases and 832 controls.The meta-analysis results indicated that comprehensive community intervention effectively prevented severe mental patients from recurrence; the risk of the disease recurrence for intervention group was 0.322 compared to the control group during the follow-up period(odds ratio OR=0.322, 95% confidence interval 95% CI:0.241, 0.430).The funnel plot showed no significant asymmetry, with the P-values of 0.283 and 0.151 for Begger's and Egger's test, and no significant publication bias was observed for the included articles; meanwhile, sensitivity analysis indicated that the results of the analysis were relatively stable.Conclusion Comprehensive community intervention has significant positive effect on reducing recurrence rate among severe mental patients and is helpful to promote the accessibility of mental health service and reduce social and family burden of severe mental disease.

     

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