Abstract: Objective To analyze the status of compensation for adverse events following preventive vaccination of category A vaccines in Guangdong province during 2012 to 2013.Methods Case studies were conducted and descriptive epidemiologic method was used in the analyses.Results A total of 66 cases of adverse events following free preventive vaccination of category A vaccines were reported in 35 counties or districts of 18 prefectures in Guangdong province from 2012 to 2013 and the total compensation for the adverse events was 5.02 millions Yuan(RMB).Of the compensation, 63.74% were for the related disabilities of the cases(4.92 millions Yuan).The average amount of compensation to each case was about 74 500 Yuan and the first three higher average compensation amount were for the adverse events caused by the vaccination of oral poliovirus attenuated live vaccine(OPV) (29 730 Yuan), measles attenuated live vaccine(MV) (17 010 Yuan), and group A meningococcus polysaccharide vaccine(MPV-A) (12 670 Yuan).The average time for the verification of compensation application was 47 working days.Conclusion The average compensation amount for the adverse events following free preventive vaccination was 74.5 thousands Yuan in Guangdong province in 2012 to 2013, and the compensation amount was lower than the upper limit of the compensation for 95.45% of the cases.