Abstract: Objective To analyze the epidemic characteristics of hepatitis E(HE) in Zhenhai district of Ningbo municipality and to provide a basis for implementing preventive plan.Methods Descriptive epidemiological method was adopted to analyze the data on reported HE cases in Zhenhai district from 2005 through 2014.Results During the 10-year period, totally 141 hepatitis E cases was reported;the average annual incidence of HE was 2.06/100 000 and the annual incidence was the highest(5.02/100 000) in 2014.More HE cases(36.17%) were reported from February to April in a year and the majority(87.94%) of the reported cases were aged 30-70 years;of the reported cases, 38.30% were farmers and the male to female ratio of the reported cases was 2.38:1.Conclusion Under the condition of without specific intervention, the incidence of hepatitis E showed an increasing trend and incident peaks every 3 to 4 years between 2005 and 2014 in Zhenhai district of Ningbo municipality.