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杨维维, 刘沛, 巢健茜, 承晓华. 社区干预对高血压患者血压影响meta分析[J]. 中国公共卫生, 2016, 32(5): 712-715. DOI: 10.11847/zgggws2016-32-05-42
引用本文: 杨维维, 刘沛, 巢健茜, 承晓华. 社区干预对高血压患者血压影响meta分析[J]. 中国公共卫生, 2016, 32(5): 712-715. DOI: 10.11847/zgggws2016-32-05-42
YANG Wei-wei, LIU Pei, CHAO Jian-qian.et al, . Effectiveness of community interventions on blood pressure control among hypertensives-a meta-analysis[J]. Chinese Journal of Public Health, 2016, 32(5): 712-715. DOI: 10.11847/zgggws2016-32-05-42
Citation: YANG Wei-wei, LIU Pei, CHAO Jian-qian.et al, . Effectiveness of community interventions on blood pressure control among hypertensives-a meta-analysis[J]. Chinese Journal of Public Health, 2016, 32(5): 712-715. DOI: 10.11847/zgggws2016-32-05-42

社区干预对高血压患者血压影响meta分析

Effectiveness of community interventions on blood pressure control among hypertensives-a meta-analysis

  • 摘要: 目的 评价社区干预对高血压患者血压的影响,为高血压的预防控制提供参考依据。方法 检索中国知网(CNKI)数据库、维普中国科技期刊数据库(VIP)、万方数据库、中国生物医学文献数据库(CBM)、PubMed数据库和Web of Science数据库,全面收集社区干预对高血压患者血压影响的相关研究;采用Stata 12.0软件对纳入的文献进行meta分析,以干预后试验组和对照组高血压患者的收缩压和舒张压为评价指标,综合评价社区干预对高血压患者血压水平的干预效果。结果 最终纳入18篇文献(中文文献11篇,英文文献7篇),累计干预人数4716例,对照人数3545例;meta分析结果显示,干预后社区干预组高血压患者收缩压(SMD=-0.65,95%CI=-0.89~-0.41)和舒张压(SMD=-0.51,95%CI=-0.71~-0.31)均低于对照组,差异均有统计学意义(均P<0.001);敏感性分析结果显示本研究结果具有良好的稳定性;Egger线性回归法结果显示,收缩压变化存在发表偏倚(t=-2.77,95%CI=-8.00~-1.06,P=0.014),舒张压不存在发表偏倚(t=-1.13,95%CI=-4.98~1.54,P=0.277)。结论 社区干预可降低高血压患者的收缩压和舒张压,但这一结论需要大样本高质量的随机对照试验进一步予以证实。

     

    Abstract: Objective To evaluate the influence of community intervention on blood pressure control among hypertension patients with meta-analysis.Methods Related articles published between 2004 and 2014 were searched through China National Knowledge Infrastructure(CNKI), VIP Chinese Science and Technology Periodical Database(VIP), Wanfang Database(Wanfang), Chinese Biomedical Literature Database(CBM), PubMed, and Web of Science Databases, and selected according to inclusion and exclusion criteria.The systolic and diastolic blood pressure for intervention group and the control group after community-based intervention were chosen as indicators.Stata 12.0 software was employed in the meta-analysis.Results A total of 18 articles met inclusion criteria.Meta-analysis showed that there were statistically significant differences between the community intervention group and the control group in systolic blood pressure(standardized mean differenceSMD=-0.65, 95% confidence interval(95% CI):-0.89, -0.41);P<0.001), and diastolic blood pressure(SMD=-0.51, 95% CI:-0.71, -0.31;P<0.001).Sensitivity analysis revealed that the results of this meta-analysis were stable.Conclusion The meta-analysis shows that systolic and diastolic blood pressure decrease after community interventions among hypertension patients but large-scale randomized controlled trials with higher-quality are needed to confirm the effectiveness of community intervention.

     

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