Abstract: Objective To study medication adherence and its associated factors among community hypertension patients in Wuhan municipality and to provide evidences for improving the efficiency of hypertension medication. Methods A questionnaire survey was conducted among 4 106 hypertension patients recruited with cluster random sampling at 35 community health service centers and 35 township hospitals in Wuhan municipality. Results Of the patients, 48.9% (2 007) reported good adherence to antihypertensive drugs.The results of the multivariate unconditional logistic regression showed that with medical insurance for urban residents, with new rural cooperative medical insurance or other insurance system, with isolated systolic hypertension, having hypertension and other disease-related familial economic burden were risk factors of low medication adherence;whereas, female gender, aged 61 years or above, with primary school or higher education, and with the hypertension of stage Ⅲ were protective factors of medication adherence. Conclusion Medication adherence is relatively low and mainly influenced by gender, age, education level, occupation, familial monthly income, type of medical insurance, staging of hypertension, and hypertension-related disease economic burden among community hypertension patients in Wuhan municipality.