Abstract: Non-communicable chronic diseases (NCDs) is a major public health problem that endangers people's health, and NCDs management has attracted more attentions all over the world.For now, there is a great challenge for the prevention and control of NCDs in China due to the lack of individualized intervention measures.The development of big data provides a very promising strategy for the innovation of NCDs management mode.From the respect of big data, this paper analyzes the progress in big data application among populations at high-risk and NCDs patients and summarizes the challenges in the process of big data application in NCDs management.