Abstract: Objective To explore the relationship between enhanced rate of breast magnetic resonance imaging (MRI) and clinicopathologic characteristics of breast cancer and to provide references for diagnosis of breast cancer.Methods Medical records of 103 pathologically confirmed female breast cancer patients having received MRI were collected from Sun Yat-sen Memorial Hospital Affiliated to Sun Yat-sen University from January 2014 to January 2016.The correlation between enhanced rate of MRI and clinicopathologic characteristics of breast cancer was analyzed.Results The average MRI enhanced rate of the patients was 141.40±77.96%,166.99±83.99%,174.96±84.98%,176.59±84.28%,171.79±80.61%,and 170.26±79.35% at 0.5,1,2,3,4,and 5 minutes after the injection of contrast agent,respectively.There were significant differences in the MRI enhance rate among the patients with different size of breast cancer at 0.5,1,2,3,4,and 5 minutes and among the patients with various molecular biological type and clinic stage of the tumor at 0.5 minute after the injection of contrast agent (P<0.05 for all).Conclusion The size of breast cancer has impacts on the MRI enhanced rate at various time points after the injection of contrast agent and molecular type and clinical stages also correlate with the MRI enhanced rate among female breast cancer patients.