Abstract: Objective To explore the association of satisfaction to school life with depressive and anxious symptoms among middle school students,and to provide evidences for mental health education in the students.Methods A total of 3 197 boys and girls were recruited from 2 middle schools in Shaoxing city.Depression Self-Rating Scale for Children (DSRSC) and Screen for Child Anxiety Related Emotional Disorders (SCARED) were used to assess the mental health status,and the satisfaction to school life was evaluated with School Life Satisfaction Rating Questionnaire for Adolescents (SLSRQA) among the students.Results The prevalence of dissatisfaction to school life,depression,and anxiety were 24.55%,38.04%,and 19.74%,respectively.The Pearson correlation coefficients between satisfaction to school life and depression,anxiety were -0.378 and -0.182 (P<0.001).The scores of depression and anxiety symptoms were significantly decreased with the increase of the score of the satisfaction to school life (P<0.001).The results of multivariate logistic regression showed that depression and anxiety were the risk factors of dissatisfaction to school life,with the odds ratios of 2.830 (95% confidence interval:2.353-3.404) and 1.396 (1.130-1.725),respectively.Conclusion The status of depression and anxiety is serious among middle school students in Shaoxing city.There are statistic correlations between satisfaction to school life and negative emotions.