高级检索
王海丽, 陆红梅, 罗业飞, 热依汗古丽·买买提, 熊海燕, 郑东鸣, 孙晓冬, 郑英杰. 上海市松江区中小学生乙型肝炎血清流行病学调查[J]. 中国公共卫生, 2017, 33(2): 242-244. DOI: 10.11847/zgggws2017-33-02-19
引用本文: 王海丽, 陆红梅, 罗业飞, 热依汗古丽·买买提, 熊海燕, 郑东鸣, 孙晓冬, 郑英杰. 上海市松江区中小学生乙型肝炎血清流行病学调查[J]. 中国公共卫生, 2017, 33(2): 242-244. DOI: 10.11847/zgggws2017-33-02-19
shu
WANG Hai-li, LU Hong-mei, LUO Ye-fei.et al, . Seroprvalence of hepatitis B virus among primary and high school students in Songjiang district of Shanghai municipality[J]. Chinese Journal of Public Health, 2017, 33(2): 242-244. DOI: 10.11847/zgggws2017-33-02-19
Citation: WANG Hai-li, LU Hong-mei, LUO Ye-fei.et al, . Seroprvalence of hepatitis B virus among primary and high school students in Songjiang district of Shanghai municipality[J]. Chinese Journal of Public Health, 2017, 33(2): 242-244. DOI: 10.11847/zgggws2017-33-02-19
shu

上海市松江区中小学生乙型肝炎血清流行病学调查

Seroprvalence of hepatitis B virus among primary and high school students in Songjiang district of Shanghai municipality

    摘要
  • 摘要: 目的 了解上海市松江区中小学生乙肝病毒（HBV）感染现状，为中小学生乙型肝炎的预防控制提供参考依据。方法 于2015年3-5月，采用随机整群抽样方法在上海市松江区抽取2 280名中小学生进行问卷调查，并采集血样进行乙肝病毒表面抗原（HBsAg）、乙肝病毒表面抗体（HBsAb）、乙肝病毒核心抗体（HBcAb）、乙肝病毒e抗原（HBeAg）和乙肝病毒e抗体（HBeAb）检测。结果 上海市松江区2 280名中小学生乙肝疫苗接种率为99.87%，HBsAg、HBsAb、HBcAb、HBeAg和HBeAb阳性率分别为0.57%、26.67%、9.39%、0.22%和0.18%。不同特征中小学生比较，男生HBcAb阳性率（7.53%）低于女生（11.34%）；年龄6~10岁中小学生HBsAg阳性率（34.55%）均高于11~15岁学生（26.04%）和16~20岁学生（21.86%）；小学生HBsAb阳性率（31.45%）均高于初中生（23.26%）和高中生（22.01%）；高中生HBcAb阳性率（11.54%）均高于小学生（9.23%）和初中生（6.34%）；本地户籍中小学生HBsAg、HBsAb和HBeAg阳性率（0.33%、19.89%和0）均低于外地户籍学生（1.03%、39.77%和0.64%），HBcAb阳性率（10.38%）高于外地户籍学生（7.46%），差异均有统计学意义（均P<0.05）。结论 上海市松江区中小学生乙肝接种率较高，HBsAg阳性率已降至<1%。

     

    Abstract: Objective To examine changes in serum markers of hepatitis B virus (HBV) infection among students in primary and high schools in Songjiang district of Shanghai municipality 23 years after the inclusion of HBV vaccine in the nationwide Expanded Program of Immunization.Methods A cluster sampling survey with questionnaires and blood collection was done among 2 280 students in primary and high schools in Songjiang district.All serum samples were detected for HBV markers with enzyme-linked immunosorbent assay (ELISA).Results The ages of the 2 280 students surveyed ranged between 6 and 20 years.The overall prevalence of hepatitis B surface antigen (HBsAg) was 0.57% (13/2 280),with a lower prevalence of 0.33% (5/1 503) among the students with registered residence in Shanghai municipality than that of 1.03% (8/777) among the students without registered local residence.The overall prevalence of hepatitis B surface antibody (HBsAb) and hepatitis B core antibody (HBcAb) were 26.67% and 9.39%,respectively.The prevalence of HBsAb decreased first and then increased with the increment of age of the students,with the lowest prevalence rate of 15.7% among the students aged 17 years.Conclusion The prevalence of HBV has been reduced significantly among primary and high school students in Shanghai municipality.

     

    • HTML全文
    • 参考文献(21)
    • 相关文章
    • 施引文献
  • 资源附件(0)

/

返回文章
返回