Abstract: With the increasing coverage and data collection of Children Immunization Information System (CⅡS),more effective and sufficient utilization of the data from CⅡS needs to be further improved to promote the children's vaccination and related health care.In this paper,the domestic and foreign utilization of CⅡS data were reviewed and some expectations and challenges about the future utilization of vaccination data from CⅡS were discussed to provide recommendations for future research.