湖北省2013年城乡居民血脂异常患病率及血脂水平和比值分布特征比较

潘敬菊; 何田静; 张岚; 唐雨萌; 李茜; 张庆军

doi:10.11847/zgggws2017-33-10-06

湖北省2013年城乡居民血脂异常患病率及血脂水平和比值分布特征比较

Dyslipidemia prevalence and serum lipid profiles and ratios among urban and rural residents in Hubei province,2013:a comparison analysis

摘要

摘要: 目的了解湖北省2013年城乡居民血脂异常患病率及血脂水平和比值分布特征差异，为血脂异常的防制工作提供科学依据。方法于2013年7—10月采用多阶段整群随机抽样方法，在湖北省疾病监测点系统覆盖的10个县（市、区）抽取5 926名≥18周岁城乡居民进行问卷调查和实验室检测。利用SAS 9.2基于设计的复杂抽样模块进行统计分析。结果经复杂加权计算后，湖北省2013年城乡居民血脂异常患病率为32.7%，其中高总胆固醇（TC）血症、高甘油三酯（TG）血症、高低密度脂蛋白胆固醇（LDL-C）血症和低高密度脂蛋白胆固醇（HDL-C）血症患病率分别为4.5%、12.3%、5.8%和21.6%。2013年湖北省城乡居民血清中TC、TG、LDL-C、HDL-C和非高密度脂蛋白胆固醇（non-HDL-C）的水平分别为（4.55±0.09）、（1.44±0.05）、（2.76±0.07）、（1.35±0.04）和（3.20±0.07）mmol/L。不同地区居民比较，城市居民TG水平（1.57±0.06）mmol/L高于农村居民（1.26±0.03）mmol/L，HDL-C水平（1.28±0.02）mmol/L低于农村居民（1.46±0.06）mmol/L，差异均有统计学意义（均P<0.01）；城市不同性别居民比较，男性居民TG和non-HDL-C水平（1.82±0.09）和（3.34±0.07）mmol/L均高于女性居民（1.30±0.04）和（3.11±0.06）mmol/L，HDL-C水平（1.21±0.02）mmol/L低于女性居民（1.35±0.03）mmol/L，差异均有统计学意义（均P<0.01）；农村不同性别居民比较，男性居民HDL-C水平（1.41±0.05）mmol/L低于女性居民（1.51±0.07）mmol/L，差异有统计学意义（P<0.01）。血脂比值TC/HDL-C、LDL-C/HDL-C、non-HDL-C/HDL-C和TG/HDL-C分别为3.67、2.20、2.67和1.45；其中，男性居民分别为3.93、2.33、2.93和1.81，均高于女性居民的3.41、2.07、2.41和1.08，城市居民分别为3.85、2.29、2.85和1.69，均高于农村居民的3.39、2.07、2.39和1.07，差异均有统计学意义（均P<0.01）。结论湖北省城乡居民血脂异常率较高；城市居民TG水平高于农村居民，HDL-C水平低于农村居民；各项血脂比值男性均高于女性，城市居民均高于农村居民。

Abstract: Objective To compare the dyslipidemia prevalence,serum lipid profiles and ratios between urban and rural residents in Hubei province in 2013 and to provide evidences for the prevention and control of dyslipidemia.Methods Questionnaire survey and laboratory test were conducted among 5 926 urban or rural residents aged 18 and over selected with multi-stage cluster random sampling from 10 disease surveillance points (DSPs) in Hubei province in 2013.SAS 9.2 was used for statistical analysis through design-based complex sampling module.Results After complex weighting,the overall dyslipidemia prevalence rate in urban and rural residents in Hubei province was 32.7%.The prevalence rates for high total cholesterol (TC),triglyceride (TG),low density lipoprotein-cholesterol (LDL-C) and low high density lipoprotein-cholesterol (HDL-C) were 4.5%,12.3%,5.8%,and 21.6%,respectively.The level of serum TC,TG,LDL-C,HDL-C and non-HDL-C were 4.55±0.09,1.44±0.05,2.76±0.07,1.35±0.04,and 3.20±0.07 mmol/L,respectively.The urban residents had significantly higher levels of serum TG (1.57±0.06 vs.1.26±0.03 mmol/L),lower levels of serum HDL-C (1.28±0.02 vs.1.46±0.06 mmol/L) than rural residents (both P<0.01).The male urban residents had higher levels of TG (1.82±0.09 vs.1.30±0.04 mmol/L),non-HDL-C (3.34±0.07 vs.3.11±0.06 mmol/L),lower levels of serum HDL-C (1.21±0.02 vs.1.35±0.03 mmol/L) than female urban residents (P<0.01 for all).The male rural residents had a lower level of serum HDL-C (1.41±0.05 vs.1.51±0.07 mmol/L) than female rural residents(P<0.01).The ratios of TC/HDL,LDL/HDL,non-HDL/HDL,TG/HDL were 3.67,2.20,2.67,and 1.45,respectively,which were all higher among the male residents (3.93,2.33,2.93,and 1.81) than among the female residents (3.41,2.07,2.41,and 1.08) and higher among urban residents (3.85,2.29,2.85,and 1.69) than among rural residents (3.39,2.07,2.39,and 1.07),with statistically differences.Conclusion The dyslipidemia prevalence was high among residents in Hubei province.Compared to rural residents,urban residents showed higher serum TG and lower serum HDL-C.All lipid ratios were higher in male residents than in female residents and higher in urban residents than in rural residents.

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