Effect on Anticomplementary Competence in the Sera of the Rat with Arsenic Poisoning and the Toxicopexis by Selenium

To explore the effect of arsenic to immunefunction by measuring anticomplementary competence (ACC) in sera of rats.The ACC of rats arsenic poisoning was significantly lower than that of the control rats(P<0.05).The ACC of arsenic+selenium group were significantly higher than that of arsenic group(P<0.05), and had no significant difference with control group(p>0.05). There was no significant difference in sera ACC between the two arsenic+selenium group(p>0.05).These results suggested that the lower ACC might be one of the mechanism responsible for the disorder of immune adjustment induced by the arsenic poisning,and the selenium could have a toxicopexis effect.